The computer program for the generation of Wiswesser Line Notation (WLN) has been extended to include polyfused rings, methyl contraction rules, chain of two ring systems, some perifused rings, some chelates, and some metallocenes. Salts and ions are also handled, but in a different manner than what is normally found. (10 references) (Author/NH)

This paper discusses the encoding and decoding of a Wiswesser Line Notation (WLN) with exactness suitable for a computer, and is an outgrowth of a computer program now in operation at NIH which automatically encodes and decodes WLN. (5 references) (Author/NH)

An indexing system for chemistry and technology of macromolecular substances is sketched out, whose characteristics are convenience of use and low cost. The selection mechanism consists of a set of optical coincidence cards. The selection is a result of 15 years experience in the German Plastics Institute. (13 references) (Author)

A technique for structuring and searching a large file of chemical structures is presented. The technique involves generating a nested, structured tree based on the Wiswesser analysis of chemical structures. An important virtue of the tree is the rapid and inexpensive file updating. (9 references) (Author/NH)

An improved scientific information system is proposed involving dissemination of abstracts to indivduals by core abstract services followed by publication and distribution of individual articles. (Author/JB)

Described is a storage and retrieval system developed for a pharmaceutical firm for internal document control. There is a thesaurus and four data files. Two important features include coordinate indexing using roles and links as well as the use of Wiswesser Line Notation for storing compounds. (3 references) (Author/SJ)

Progress in the development of advanced chemical information systems in the United Kingdom is briefly described. (8 references) (Author)

A prototype of an interactive, conversational mass spectral search system, developed at the National Institutes of Health, has been tested since September 1971 and is now being used by more than 200 scientists in the U.S. and Canada, and will soon be used by the international mass spectrometry community. (17 references) (SJ)

Conversion of the Chemical Abstract Service scientific literature data base from Standard Distribution Format to a center-oriented file format, STF, is described. A tape file format is described in which variable length logical records, possibly longer than the blocksize, may be stored safely. (7 references) (Author/NH)

While scientific progress has developed toward interdisciplinary and broad-scope technologies, information resources have become increasingly fragmented and specialized. What is needed is more attention to the intellectual input and output of information systems, focusing on actual user needs. (2 references) (Author/NH)

That the value of information and, hence, the design of information systems, whether for a company, a university, a learned society, or an individual, is in the early stages of a significant change in structure is demonstrated in this paper. (5 references) (Author/NH)

In 1969 the American University offered a Workshop in Chemical Substructure Information Handling Systems. Topics covered in the courses are described. (Authors)

A mail survey to purchasers of National Standard Reference Data System (NSRDS) publications gave evidence that NSRDS publications were helpful to users in meeting their data requirements. Specific uses and benefits were identified. The greatest use of NSRDS publications was in connection with basic research. (3 references) (Author/NH)

Almost three million records covering approximately 175,000 chemical compounds and involving multiple disciplines have been recorded in the Army Antimalarial Drug Program. Maximum compartmentalization of files together with a complete method of interfacing files and a unique number system has made it possible to manage this system. (2 references)…

A collection of computer programs to do chemical information retrieval are described in terms of the interactions between the computer and the chemist. In interacting with the computer, the chemist can graphically specify two-dimensional structures as queries and view structures as search results. (18 references) (Author/NH)