Some countries have strong culturally rooted practices and policies to incentivize their PhD candidates to develop their doctoral studies abroad. Their programs provide cultural and methodological diversity opportunities and globally oriented career prospects. In the last years, many of those countries are increasingly developing their own domestic doctoral programs, which may offer career benefits due to their strong connections to the local research and academic environment. The career paths of 126 PhD holders working in Paraguay, a country in which doctoral studies abroad intersect with national-based doctoral programs, were examined using the ECRID survey. The perceptions of those who completed their doctoral studies domestically and those who studied abroad were compared in terms of the usefulness of the skills provided by their respective PhD programs. The results showed that most PhD holders in Paraguay work full-time in the academic sector. The percentage of PhD holders employed in non-academic roles reflects the diversity of career options available to PhDs holders in the Paraguayan labour market. Furthermore, results indicated how the participants re-signified the skills acquired during the doctoral program to adapt them to various professional settings. This process underscores the emerging demands of the current labour market and the necessity for universities to adjust doctoral training models to better equip graduates for diverse professional paths. This adjustment includes institutional support to reduce cultural shock and subsequent burnout levels. Pioneering results from the Paraguayan context provide empirical evidence to enrich the reflection on the resources and opportunities for PhD holders at both structural and organizational levels.