Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics. Enzyme kinetics is a staple of biochemistry curricula and other disciplines, from molecular and…

This article seeks to provide researchers and practitioners in laboratory education, particularly those involved in the curriculum design and implementation of teaching laboratories at university level, with a conceptual framework and a working model for an integrated assessment of learning domains, by attending to a more holistic approach to…

Discussed are the potential hazards associated with nitric acid, inorganic and organic nitrate salts, alkyl nitrates, acyl nitrates, aliphatic nitro compounds, aromatic nitro compounds, and nitration reactions. (CW)

Describes the necking of polymer sheets that occurs when they are stretched. Discusses the effect and the mechanisms of necking. Lists four references. (YP)

Discusses the role of dogs in research, considering their use in studies related to: behavior; aging; anesthesia; gastrointestinal surgery; the brain; organ transplants; radiobiology; trauma and shock; arterial diseases; hemophelia; ophthalmology; diabetes; nutrition; cancer; lupus; cyclic neutropenia; thyroiditis; hepatitis; skeletal system,…

Describes the Tardigrada as a group of animals suitable for close study in project work. Gives reasons for their suitability and an illustrated identification key. Discusses possible investigations into the ecology and physiology of tardigrades. (Author/CW)

Discussed are the two sides to the question of laboratory dissections. Alternatives to dissection are proposed as well as the importance of incorporating dissections in a science curriculum. (KR)

Discusses issues and the public's concerns related to using laboratory animals for research purposes. Indicates that several perceptions (such as recognizing that the public's attitudes toward respect for animal life are no more irrational than many broader attitudes toward the sacredness of life) characterize the most responsible of recent…

Reports an experiment for examining protein-ligand binding using the enzyme carbonic anhydrase. Describes the experimental procedures consisting of the syntheses of an azosulfonamide and its complex formation with carbonic anhydrase. (YP)

The Prime Minister's Committee on Natural Science in Education in Great Britain reported in 1918 that "...in many schools more time is spent in laboratory work than the results obtained can justify." Seventy years later this conclusion can often still be drawn. This is particularly a problem in open distance education where laboratory practicals,…

Discusses the characteristics and development of a computer simulation laboratory for educational administration research at the University of Wisconsin at Madison, and reviews an experimental study performed at the laboratory on stress in decision-making. Explores how simulations provide researchers access to experimental conditions unavailable…

Examines the extent to which issues related to animal experimentation are in conflict and proposes choices that might least comprise them. These issues include animal well-being, human well-being, self-interest of science, scientific validity and responsibility, progress in biomedical and behavioral science, and the future quality of medical care.…

Describes a general purpose microcomputer-based system designed to support small-scale experimentation in the physical sciences in student laboratories. System requirements, teacher reactions, and educational implications are discussed; design criteria are established; and examples are given of the system's application to some simple experiments.…

To demonstrate that properly designed laboratory instruction does provide affective and higher order learning benefits, an experiment was carried out in two replications. The subjects were 80 students enrolled in General Microbiology at Wallace Community College, Alabama. Students were randomly assigned to experimental and control groups. The…

Discusses general construction principles for miniaturized laboratory glassware. Describes a prototype experimental kit that allows the carrying out of all standard laboratory operations and discusses a trial use of the equipment with students 16- to 17-years-old. (CW)