A renewed experimental procedure for the unknown carbonyl experiment has been developed using hydrazone synthesis, thin layer chromatography (TLC) analysis, and melting point determination to differentiate between structurally similar ketones and aldehydes in undergraduate organic chemistry practical courses. Benzaldehyde, p-tolualdehyde,…

This paper outlines a comprehensive teaching laboratory course program that centers on titration analysis, a timeless and essential technique in analytical chemistry spanning various disciplines, such as environmental science, medicine, and industry. In these fields, titration analysis is paramount for determining the concentrations of substances…

[This paper is part of the Focused Collection on Instructional labs: Improving traditions and new directions.] In this paper, we describe the results of a research project whose goals were to (1) develop and implement video-based experimental investigations using the Investigative Science Learning Environment (ISLE) approach and (2) study how…

Experimental teaching is an important part of postgraduate training in basic and clinical medicine. While primary cell isolation and identification are among the most important research techniques for medical graduate students, most graduate students do not understand and master these techniques before starting their research experience. In…

A drug discovery project has been successfully implemented in an advanced undergraduate organic chemistry laboratory. In the laboratory, a five-step synthetic sequence is used to prepare five analogues of 13-phenyl-1-tridecanol. These compounds are key precursors in the synthesis of 2-oxo-14-phenyltetradecanes. This class of compounds, isolated…

The aldol condensation reaction is one of the many synthesis reactions carried out in second semester organic chemistry laboratories. This reaction was integrated into a novel experiment requiring students to synthesize dibenzalace tone derivatives using the crossed-aldol condensation by reacting different types of benzaldehyde derivatives with…

A traditional laboratory course with the primary learning outcome of improving students' theoretical knowledge has received much criticism over the years due to the lack of evidence that these goals have achieved. We report our efforts to redesign a traditional first-year organic and inorganic (also known as synthetic) laboratory course from…

Interdisciplinary experiments within chemistry are very important for the improvements in the overall quality of the education received by students. In this work, we describe an interdisciplinary experiment that was successfully completed by undergraduate students. This training integrates multiple disciplines including natural product medicinal…

[This paper is part of the Focused Collection on Instructional labs: Improving traditions and new directions.] Research on nontraditional laboratory (lab) activities in physics shows that students often expect to verify predetermined results, as takes place in traditional lab activities. This understanding of what is taking place, or…

This paper introduces hands-on curricular modules integrated with research in atmospheric ice nucleation, which is an important phenomenon potentially influencing global climate change. The primary goal of this work is to promote meaningful laboratory exercises to enhance the competence of students in the fields of science, technology,…

Nowadays, novel Biochemistry lab techniques are being introduced at a very fast pace in scientific research. This requires development of new labs for undergraduate Biochemistry courses to equip the students with up-to-date techniques. However, the time limit of Biochemistry labs for undergraduate students represents a major obstacle. This article…

A revised version of a traditional physical chemistry laboratory experiment has been developed to enhance student discussion in the laboratory and to improve students' connections between physical chemistry concepts and real molecular systems. In this experiment, students explore the keto-enol tautomerization of 2,4-pentanedione. However, unlike…

Enzymes are widely applied in different industries, like pharmaceutical, food, biofuel, and waste valorization. However, the enzyme operating conditions are very limited. So, in most industrial processes, enzymes are not efficient, due to the use of harsh conditions, like organic solvents, extreme pH, and temperature. Immobilization arises as a…

Given the importance of self-healing polymers for chemistry education, herein, we introduce our latest research results in self-healing materials based on thioctic acid into undergraduate chemistry laboratory. In this experiment, a natural small molecule, thioctic acid (TA), and a few other commercially-available reagents have been used to make a…

A research-style laboratory experiment for advanced undergraduate students is described, which includes the synthesis, characterization, and properties (porosity, stability, amphipathy) testing of the composite [Cu[subscript 2](BTC)[subscript 4/3](H[subscript 2]O)[subscript 2][subscript 6][HPW[subscript 12]O[subscript 40]·(C[subscript…