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Joana F. C. Silva; Ma´rio T. S. Rosado; Teresa M. R. Maria; Pedro S. Pereira Silva; Manuela Ramos Silva; M. Ermelinda S. Euse´bio – Journal of Chemical Education, 2023
The concept of co-amorphous systems is introduced in an integrated laboratory experiment, designed for advanced chemistry students, using solvent-free, environmentally friendly mechanochemistry. The dual-drug naproxen-cimetidine co-amorphous system (NPX-CIM) is investigated as an example of the emergent field of medicinal mechanochemistry.…
Descriptors: Laboratory Experiments, Chemistry, Science Instruction, Pharmacology

Peer reviewed
