We created a novel laboratory experience where undergraduate students explore the techniques used to study protein misfolding, unfolding, and aggregation. Despite the importance of protein misfolding and aggregation diseases, protein unfolding is not typically explored in undergraduate biochemistry laboratory classes. Yeast alcohol dehydrogenase…

Colloidal stability is one of the most important criteria in the application strategy of colloidal nanoparticles in the continuous phase. The branches include ecology, involving coagulation as a purification method; medicine as nanocarriers; biology as blood coagulation, etc. A chemist versed in these concepts is a high-performing chemist in…

A comprehensive chemistry laboratory experiment, including the synthesis of Pt/Al[subscript 2]O[subscript 3] catalysts at different conditions, structure characterization, and the real-world application exploration, has been designed for upper-division undergraduate and graduate students as an expansion and improvement of the professional…

Spectroscopic characterization of molecules is typically reinforced in the organic chemistry teaching laboratory via the analysis of reaction products by NMR and IR, and initial coverage of these topics can include experiments involving the identification of unknown compounds. To combine the unknown identification component with common laboratory…

Learning in chemistry laboratories has long been challenging due to the complex nature of the learning environment and tasks that students engage with. Therefore, it is important to develop useful tools for prelab and follow-up activities besides the hands-on lab time for better management of the learners' cognitive load. In this paper, we…

"Copper to Silver to Gold: The Alchemist's Dream" is an experimental demonstration performed in many schools that involves Zn plating on a Cu coupon to induce brass plating. In this study, a novel method to achieve uniform plating is proposed using a 2.0mol/L ZnCl[subscript 2] aqueous solution, sodium dodecyl sulfate, and Al foil. This…

Titration is an important experimental skill that every chemistry educator and learner must master. Titration is often the method of choice in the science laboratory courses in secondary and postsecondary schools. During acid-base titration, chemistry learners are always told about salt formation. However, a practical visualization of the salt…

We developed a single crystal X-ray crystallography experiment based on the crystal structure of sucrose (table sugar), and a more challenging experiment using Epsom salt. Both crystals are readily available in X-ray quality crystalline form. In these experiments, students mounted a crystal on a MiTeGen loop and analyzed it using a Rigaku XtaLAB…

Both nanopore-based DNA sequencing and CRISPR/Cas-based gene editing represent groundbreaking innovations in molecular biology and genomics, offering unprecedented insights into and tools for working with genetic information. For students, reading, editing, and even writing DNA will be part of their everyday life. We have developed a laboratory…

The pharmaceutical and medicine manufacturing industry has become the largest industrial sector for the employment of chemists, indicating a need for experiments with a pharmaceutical sciences context in the undergraduate chemistry curriculum. In the pharmaceutical industry, testing drug dissolution is a key analytical task for solid oral dosage…

This paper outlines a comprehensive teaching laboratory course program that centers on titration analysis, a timeless and essential technique in analytical chemistry spanning various disciplines, such as environmental science, medicine, and industry. In these fields, titration analysis is paramount for determining the concentrations of substances…

By hosting a college students' laboratory skills contest, we provide an interesting activity for students to cultivate good laboratory practices and thereby improve their laboratory skills. The substance of this contest is the detection of the hardness of water, which involves numerous laboratory skills such as solution preparation, weight by…

Real-time quantitative PCR is a technique used to monitor the PCR reaction in real time. RT-qPCR is broadly classified into two types based on its purpose: absolute and relative quantification. Absolute quantification is used in a wide array of fields such as microbiology, food technology, and biotechnology to quantify the microbiological…

A student experiment that uses QuEChERS (quick, easy, cheap, effective, rugged, and safe) methodology for extraction and HPLC for quantitative determination of tocopherols from seeds and nuts is described here. Chromatographic separation is achieved by using a pentafluorophenyl stationary phase which gives enhanced separation of the tocopherols…

The concept of co-amorphous systems is introduced in an integrated laboratory experiment, designed for advanced chemistry students, using solvent-free, environmentally friendly mechanochemistry. The dual-drug naproxen-cimetidine co-amorphous system (NPX-CIM) is investigated as an example of the emergent field of medicinal mechanochemistry.…