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Kwapis, Janine L.; Jarome, Timothy J.; Helmstetter, Fred J. – Learning & Memory, 2015
The extinction of delay fear conditioning relies on a neural circuit that has received much attention and is relatively well defined. Whether this established circuit also supports the extinction of more complex associations, however, is unclear. Trace fear conditioning is a better model of complex relational learning, yet the circuit that…
Descriptors: Brain Hemisphere Functions, Learning Processes, Conditioning, Role
Gafford, Georgette M.; Parsons, Ryan G.; Helmstetter, Fred J. – Learning & Memory, 2005
Benzodiazepines have been useful tools for investigating mechanisms underlying learning and memory. The present set of experiments investigates the role of hippocampal GABA[subscript A]/benzodiazepine receptors in memory consolidation using Pavlovian fear conditioning. Rats were prepared with cannulae aimed at the dorsal hippocampus and trained…
Descriptors: Animals, Drug Use, Learning Processes, Brain Hemisphere Functions