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Direct linkNavakkode, Sheeja; Sajikumar, Sreedharan; Korte, Martin; Soong, Tuck Wah – Learning & Memory, 2012
The dopaminergic modulation of long-term potentiation (LTP) has been studied well, but the mechanism by which dopamine induces LTP (DA-LTP) in CA1 pyramidal neurons is unknown. Here, we report that DA-LTP in basal dendrites is dependent while in apical dendrites it is independent of activation of L-type voltage-gated calcium channels (VDCC).…
Descriptors: Basal Reading, Logical Thinking, Neurological Organization, Cognitive Processes
Sajikumar, Sreedharan; Navakkode, Sheeja; Frey, Julietta U. – Learning & Memory, 2008
The protein synthesis-dependent form of hippocampal long-term potentiation (late-LTP) is thought to underlie memory. Its induction requires a distinct stimulation strength, and the common opinion is that only repeated tetani result in late-LTP whereas as single tetanus only reveals a transient early-LTP. Properties of LTP induction were compared…
Descriptors: Memory, Logical Thinking, Learning Processes, Animals
