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Holl, Anna K.; Wilkinson, Leonora; Tabrizi, Sarah J.; Painold, Annamaria; Jahanshahi, Marjan – Neuropsychologia, 2012
In general, declarative learning is associated with the activation of the medial temporal lobes (MTL), while the basal ganglia (BG) are considered the substrate for procedural learning. More recently it has been demonstrated the distinction of these systems may not be as absolute as previously thought and that not only the explicit or implicit…
Descriptors: Evidence, Feedback (Response), Diseases, Patients
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Wilkinson, Leonora; Teo, James T.; Obeso, Ignacio; Rothwell, John C.; Jahanshahi, Marjan – Journal of Cognitive Neuroscience, 2010
Theta burst transcranial magnetic stimulation (TBS) is considered to produce plastic changes in human motor cortex. Here, we examined the inhibitory and excitatory effects of TBS on implicit sequence learning using a probabilistic serial reaction time paradigm. We investigated the involvement of several cortical regions associated with implicit…
Descriptors: Stimulation, Reaction Time, Matched Groups, Cognitive Processes
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Osman, Magda; Wilkinson, Leonora; Beigi, Mazda; Castaneda, Cristina Sanchez; Jahanshahi, Marjan – Neuropsychologia, 2008
The striatum is considered to mediate some forms of procedural learning. Complex dynamic control (CDC) tasks involve an individual having to make a series of sequential decisions to achieve a specific outcome (e.g. learning to operate and control a car), and they involve procedural learning. The aim of this study was to test the hypothesis that…
Descriptors: Observation, Diseases, Patients, Multimedia Instruction