Brain-derived neurotrophic factor (BDNF) has been implicated as a molecular mediator of learning and memory. The BDNF gene contains four differentially regulated promoters that generate four distinct mRNA transcripts, each containing a unique noncoding 5[prime]-exon and a common 3[prime]-coding exon. This study describes novel evidence for the…

The focus of this paper is the application of laboratory-derived principles to a more real-life situation. Specifically, a learning model is presented with the intent that principles and procedures derived from it be directly applicable to learning in the college classroom. The model presented is derived from 2 orientation to the phenomena of…

Evidnce obtained in the present experiment suggests that explanatory instructional sets preceding implosive therapy can facilitate the reduction in fear to an avoided object. (Author) Therapy

In four experiments using albino rats in an ABA fear renewal paradigm, we studied conditioned fear in the A test context following extinction in Context B. Conditioned suppression of operant responding was the index of fear. In Experiments 1-3, we found that extinguishing a feared cue in compound with a putative conditioned inhibitor of fear led…

Three mechanisms can explain second-order conditioning: (1) The second-order conditioned stimulus (CS2) could activate a representation of the first-order conditioned stimulus (CS1), thereby provoking the conditioned response (CR); The CS2 could enter into an excitatory association with either (2) the representation governing the CR, or (3) with a…

Having recently shown that extinction of conditioned fear depends on L-type voltage-gated calcium channels (LVGCCs), we have been seeking other protocols that require this unusual induction mechanism. We tested latent inhibition (LI) of fear, because LI resembles extinction except that cue exposures precede, rather than follow, cue-shock pairing.…

The present study investigated the effects of acute stress exposure on learning performance in humans using analogs of two paradigms frequently used in animals. Healthy male participants were exposed to the cold pressor test (CPT) procedure, i.e., insertion of the dominant hand into ice water for 60 sec. Following the CPT or the control procedure,…

The present study attempted to elicit covert verbalization with a bit more assurance, as compared to Gagne and Smith, and to compare the effects of instructions to covertly verbalize with instructions to talk out loud while solving problems. (Author/MS)

Three experiments compared the learning of lower-dimensional family resemblance categories (4 dimensions) with the learning of higher-dimensional ones (8 dimensions). Category-learning models incorporating error-driven learning, hypothesis testing, or limited capacity attention predict that additional dimensions should either increase learning…

The purpose of this experiment was to see if there would be a conditioning of evaluative meaning effect when a procedure was used that reduced contingency and demand awareness. The results lend support to Staats' conditioning of meaning and attitude theory. (Author/KM)

Nursery school children were shown films to vicariously condition either fear or positive emotional responses in them. The children showed a higher rate of responding to the positive stimulus. (Author/KM)

Discusses the importance of genetic and epigenetic factors in the development of the nervous system and the performances it conditions. From the perspective of rules, play, and relaxation of rules, learning and education are not considered as a kind of conditioning but as providing a content in which the cumulative expression of potential can take…

Human conditioning research shows that learning is closely related to consciously available contingency knowledge, requires attentional resources, and is influenced by language. This research suggests a cognitive model in which extinction consists of changes in contingency beliefs in long-term memory. Laboratory and clinical evidence on extinction…