The predictive ability of early consonant inventory and intentional communication on later expressive language was examined in 36 boys with fragile X syndrome (FXS). Autism symptom severity was included as a potential moderator. Participants were visited in their homes twice over a 6-year period, and mother-child interactions were videotaped,…

Studies assessing sex/gender differences in autism spectrum conditions often fail to include typically developing control groups. It is, therefore, unclear whether observed sex/gender differences reflect those found in the general population or are particular to autism spectrum conditions. A systematic search identified articles comparing…

Background: Changes in reward processing are thought to be involved in the etiology of attention-deficit/hyperactivity disorder (ADHD), as well as other developmental disorders. In addition, different forms of therapy for ADHD rely on reinforcement principles. As such, improved understanding of reward processing in ADHD could eventually lead to…

Stereotypic behavior exhibited by a third grade boy with autism was maintained by automatic reinforcement and occurrences of stereotypy were brought under stimulus control. The intervention consisted of pairing a green discriminative stimulus card (SD) with free access to stereotypy and a red card (SD absent) with vocal redirection and blocking…

In the present study, we used a probe-detection task to compare attentional allocation to the eyes versus mouth regions of the face in high-functioning boys with autism relative to normal control boys matched for chronological age and IQs. We found that with upright faces, children from both groups attended more to the eyes region than to the…

The IQ and behavior patterns on the Autism Behavior Checklist (ABC) of 25 boys were compared to blood concentrations of platelet rich plasma (PRP) serotonin. Although no correlations were found between serotonin levels and IQ or ABC scales, four individual ABC items did correlate with serotonin concentrations. (Author/DB)

This case study of two young males (ages 3 and 5) with autism who have preoccupations with feminine activities and objects addresses the establishment of gender identity in children with autism and the need for further study of the complex interplay of environmental and neurobiologic factors affecting gender identity and preoccupations in autism.…

Direct observational data were collected on the behavior of 26 elementary school-age boys with fragile X syndrome (FXS), the most prevalent inherited cause of mental retardation, during classroom academic activities. Findings indicated classroom engagement comparable to that of peers and not related to intrasubject variables such as severity of…

Functional analysis of the aggressive behavior of 2 boys (ages 10 and 12) with autism involved 20 brief functional assessment trials in the classroom under 3 conditions. Results showed a clear pattern in each child's aggressive behavior and suggested logical intervention strategies. The discrete-trial approach presented a practical, ecologically…

This paper presents a case report of a young adult Japanese male with infantile autism who also met diagnostic criteria for seasonal affective disorder and trichotillomania (compulsive hair pulling). The case report deals with difficulties in diagnosing mood disorder in such individuals, potential treatment effectiveness of valproic acid, and…

This final report reviews the second phase of a life-span study of boys with fragile X syndrome (FSX), the most common known inherited cause of mental retardation. Males with the syndrome are more severely affected than females and in males, delays are usually evident in all the developmental domains, although cognitive and communication skills…

This paper reviews the research on fragile X syndrome, the second most common cause of mental retardation related to chromosomal anomaly. It notes that far more males than females are affected by the fragile X syndrome, which typically results in craniofacial changes, delays in growth and development, speech/language difficulties, and cognitive…