Mathematics provides us with tools to capture and explain phenomena in everyday biology, even at the nanoscale. The most regularly applied technique to biology is differential equations. In this article, we seek to present how differential equation models of biological phenomena, particularly the flow through ion channels, can be used to motivate…

The major challenge of most basic schools is inadequate educational resources despite a conscious effort to constantly provide. This is a result of inaccurate data management leading to inappropriate predictions for effective planning. The actual efficiency of a system is determined by its ability to predict real-life data with speed and accuracy.…

This paper presents an application of the Kalman filter in signal processing in instrumentation systems when the conditions of the environment generate a large amount of interference for the acquisition of signals from measurement systems. The unwanted interferences make important use of the instrumentation system resources and do not represent…

It is shown that it is not easy to apply the EM algorithm to latent class models in the general case with equality constraints because a nonlinear equation has to be solved. A simpler condition is given in which the EM algorithm can be easily applied. (SLD)

A method for hierarchical agglomerative polythetic (multivariate) clustering, based on unweighted pair group using arithmetic averages (UPGMA) is compared with the original beta-flexible technique, a weighted average method. Reasons the flexible UPGMA strategy is recommended are discussed, focusing on the ability to recover cluster structure over…

The frequencies of "m" independent "p-way" contingency tables are analyzed by a model that assumes that the ordinal category data in each of "m" groups are generated from a latent continuous multivariate normal distribution. The model permits analysis of several groups of individuals simultaneously. (TJH)

A procedure is described for minimizing a class of matrix trace functions, which is a refinement of an earlier procedure for minimizing the class of matrix trace functions using majorization. Several trial analyses demonstrate that the revised procedure is more efficient than the earlier majorization-based procedure. (SLD)

A globally optimal solution is presented for a class of functions composed of a linear regression function and a penalty function for the sums of squared regression weights. A completing-the-squares approach is used, rather than calculus, because it yields global minimality easily in two of three cases examined. (SLD)

Arguments by J. Levin (1988) challenging the convergence properties of the Harman and Jones (1966) method of Minres factor analysis are shown to be invalid. Claims about the invalidity of a rank-one version of the Harman and Jones method are also refuted. (TJH)

This paper shows that redundancy maximization with J. K. Johansson's extension can be accomplished via a simple iterative algorithm based on H. Wold's Partial Least Squares. The model and the iterative algorithm for the least squares approach to redundancy maximization are presented. (TJH)

An algorithm based on the majorization theory of J. de Leeuw and W. J. Heiser is presented for fitting the slide-vector model. It views the model as a constrained version of the unfolding model. A three-way variant is proposed, and two examples from market structure analysis are presented. (SLD)

A new procedure is proposed for handling nominal variables in the analysis of variables of mixed measurement levels, and a procedure is developed for handling ordinal variables. Using these procedures, a monotonically convergent algorithm is constructed for the FACTALS method for any mixture of variables. (SLD)

The probability integral of the multivariate normal distribution (ND) has received considerable attention since W. F. Sheppard's (1900) and K. Pearson's (1901) seminal work on the bivariate ND. This paper evaluates the formula that represents the "n x n" correlation matrix of the "chi(sub i)" and the standardized multivariate…

L. A. Goodman's loglinear formulation for bi-way contingency tables is extended to tables with or without missing cells and is used for exploratory purposes. Three-way tables and generalizations of correspondence analysis are deduced, and a generalized version of Goodman's algorithm is used to estimate scores in all cases. (Author/TJH)

An algorithm for obtaining initial values for the minimization process in covariance structure analysis is developed that is more generally applicable for computing parameters connected to latent variables than the currently existing ones. The algorithm is formulated in terms of the RAM model but can be extended. (SLD)