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Belias, Michail; Rovers, Maroeska M.; Hoogland, Jeroen; Reitsma, Johannes B.; Debray, Thomas P. A.; IntHout, Joanna – Research Synthesis Methods, 2022
One of the main goals of an individual participant data meta-analysis (IPD-MA) of intervention studies is to investigate whether treatment effect differences are present, and how they are associated with patient characteristics. Examining treatment heterogeneity due to a continuous covariable (e.g., BMI or age) may be challenging, since there is…
Descriptors: Meta Analysis, Outcomes of Treatment, Prediction, Multivariate Analysis