Causal mediation analysis has gained increasing attention in recent years. This article guides empirical researchers through the concepts and challenges of causal mediation analysis. I first clarify the difference between traditional and causal mediation analysis and highlight the importance of adjusting for the treatment-by-mediator interaction…

This article presents two ways of quantifying confounding using logistic response models for binary outcomes. Drawing on the distinction between marginal and conditional odds ratios in statistics, we define two corresponding measures of confounding (marginal and conditional) that can be recovered from a simple standardization approach. We…

Mediation analysis in Single Case Experimental Designs (SCEDs) evaluates intervention mechanisms for individuals. Despite recent methodological developments, no clear guidelines exist for maximizing power to detect the indirect effect in SCEDs. This study compares frequentist and Bayesian methods, determining (1) minimum required sample size to…

Purpose: Multisite mediation studies are a cornerstone in mapping out developmental processes because they probe the mechanisms of a treatment while creating key opportunities to learn from and about variation in those mechanisms across sites. Despite the prevalence of multisite studies, a significant gap in the literature is how to plan such…

Conditional process models, including moderated mediation models and mediated moderation models, are widely used in behavioral science research. However, few studies have examined approaches to conduct statistical power analysis for such models and there is also a lack of software packages that provide such power analysis functionalities. In this…

In the article, we focused on the issues of measurement error and omitted confounders while conducting mediation analysis under experimental studies. Depending on informativeness of the confounders between the mediator (M) and outcome (Y), we described two approaches. When researchers are confident that primary confounders are included (e.g.,…

In causal mediation studies that decompose an average treatment effect into indirect and direct effects, examples of post-treatment confounding are abundant. In the presence of treatment-by-mediator interactions, past research has generally considered it infeasible to adjust for a post-treatment confounder of the mediator-outcome relationship due…

Mediation has played a critical role in developmental theory and research. Yet, developmentalists rarely discuss the methodological challenges of establishing causality in mediation analysis or potential strategies to improve the identification of causal mediation effects. In this article, we discuss the potential outcomes framework from…

Empirical studies often demonstrate multiple causal mechanisms potentially involving simultaneous or causally related mediators. However, researchers often use simple mediation models to understand the processes because they do not or cannot measure other theoretically relevant mediators. In such cases, another potentially relevant but unobserved…

When designing a study for causal mediation analysis, it is crucial to conduct a power analysis to determine the sample size required to detect the causal mediation effects with sufficient power. However, the development of power analysis methods for causal mediation analysis has lagged far behind. To fill the knowledge gap, I proposed a…

Research questions regarding how, for whom, and where a treatment achieves its effect on an outcome have become increasingly valued in substantive research. Such questions can be answered by causal moderated mediation analysis, which assesses the heterogeneity of the mediation mechanism underlying the treatment effect across individual and…

While a considerable number of studies have focused on factors driving employees to voluntarily participate in training programs, much less is known on this topic with regard to the unemployed population, in particular the older unemployed, who often are in a vulnerable labor market position due to educational deficits and skills obsolescence.…

Designs that facilitate inferences concerning both the total and indirect effects of a treatment potentially offer a more holistic description of interventions because they can complement "what works" questions with the comprehensive study of the causal connections implied by substantive theories. Mapping the sensitivity of designs to…

This study aims to study the mediation role of locus of control on the impact of learned helplessness on students' academic procrastination. Studies reported that more than 70% university students procrastinate, and one of the causes is the perception that one is vulnerable or helpless in finishing the procrastinate tasks. It was hypothesized that…

Objective: We explored the potential mediating role of willingness to experience drinking consequences and other traditional alcohol outcome predictors (descriptive norms, injunctive norms, positive alcohol expectancies) in explaining the association between college alcohol beliefs1 (CABs) and the actual experience of drinking consequences among…