The N-methyl-D-aspartate receptor (NMDAR) is thought to be essential for synaptic plasticity and learning. However, recent work indicates that the role of this receptor depends on the prior history of the research subject. For example, animals trained on a hippocampus-dependent learning task are subsequently able to acquire new information in the…

Reviews the literature on the relation between early memory development and corresponding changes in brain development of infants. Finds that an adult-like form of explicit memory emerges between 8 and 12 months of age, drawing heavily on limbic and cortical structures. Offers theoretical perspectives for studying the ontogeny of memory. (JW)

Projects that soon a complete mechanistic understanding of simple forms of learning will be available. Describes some of the recent advances in neuroscience and psychology in understanding the changes in neural circuits that occur during certain behavioral situations. Suggests that learning involves the activation of second messenger systems. (TW)