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Direct linkLin, Hui-Ching; Mao, Sheng-Chun; Gean, Po-Wu – Learning & Memory, 2006
The cannabinoid CB1 receptor has been shown to be critically involved in the extinction of fear memory. Systemic injection of a CB1 receptor antagonist prior to extinction training blocked extinction. Conversely, administration of the cannabinoid uptake inhibitor AM404 facilitated extinction in a dose-dependent manner. Here we show that bilateral…
Descriptors: Neurological Impairments, Behavioral Science Research, Animals, Fear
Celerier, Aurelie; Pierard, Christophe; Rachbauer, Dagmar; Sarrieau, Alain; Beracochea, Daniel – Learning & Memory, 2004
The present study was aimed at simultaneously determining on the same subject, the effects of stress on retrieval of flexible (contextual or temporal) or stable (spatial) information. Three behavioral paradigms carried out in a four-hole board were designed as follows: (1) Simple Discrimination (SD), in which mice learned a single discrimination;…
Descriptors: Animals, Anxiety, Models, Discrimination Learning
