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Ragozzino, Michael E.; Choi, Daniel – Learning & Memory, 2004
The present studies explored the role of the medial striatum in learning when task contingencies change. Experiment 1 examined whether the medial striatum is involved in place reversal learning. Testing occurred in a modified cross-maze across two consecutive sessions. Injections of the local anesthetic, bupivacaine, into the medial striatum, did…
Descriptors: Nonverbal Learning, Biochemistry, Neurological Impairments, Behavioral Science Research
Hebda-Bauer, Elaine K.; Watson, Stanley J.; Akil, Huda – Learning & Memory, 2005
The impact of a previously successful or unsuccessful experience on the subsequent acquisition of a related task is not well understood. The nature of past experience may have even greater impact in individuals with learning deficits, as their cognitive processes can be easily disrupted. Mice with a targeted disruption of the [alpha] and [delta]…
Descriptors: Memory, Learning Experience, Intervals, Animals