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Direct linkSerdar Karatoprak; Sadettin Burak Acikel; Abdulbaki Akyildiz; Fatma Coskun; Fatma Hümeyra Yerlikaya – International Journal of Developmental Disabilities, 2024
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder, the etiology of which has not been clearly determined yet. There is increasing evidence that synaptic and dendritic changes are involved in the etiology of ASD. The aim of this study is to determine whether serum Thrombospondin-1 and Thrombospondin-2 differ between ASD…
Descriptors: Children, Autism Spectrum Disorders, Etiology, Metabolism
Tural Hesapcioglu, Selma; Kasak, Meryem; Citak Kurt, Aysegül Nese; Ceylan, Mehmet Fatih – International Journal of Developmental Disabilities, 2019
Objective: This study aims to investigate the level of peripheral blood mononuclear cells and their ratios which may point to the immunological mechanisms involved in the etiopathogenesis of ASD. Method: The complete blood count parameters of the 45 ASD cases were compared with those of healthy controls.Childhood Autism Rating Scale (CARS) was…
Descriptors: Autism, Pervasive Developmental Disorders, Metabolism, Cytology
Essa, M. M.; Braidy, N.; Waly, M. I.; Al-Farsi, Y. M.; Al-Sharbati, M.; Subash, S.; Amanat, A.; Al-Shaffaee, M. A.; Guillemin, G. J. – Research in Autism Spectrum Disorders, 2013
Accumulating evidence suggests that oxidative stress induced mechanisms are believed to be associated with the pathophysiology of autism. In this study, we recruited 19 Omani autistic children with age-matched controls to analyze their plasma and serum redox status and the levels of ATP, NAD[superscript +] and NADH using well established…
Descriptors: Autism, Severity (of Disability), Metabolism, Foreign Countries
Hashim, Haitham; Abdelrahman, Hadeel; Mohammed, Doaa; Karam, Rehab – Research in Autism Spectrum Disorders, 2013
It has been recently shown that dysregulation of transforming growth factor-beta1 (TGF-beta1), IL-23 and IL-17 has been identified as a major factor involved in autoimmune disorders. Based on the increasing evidence of immune dysfunction in autism the aim of this study was to measure serum levels of TGF-beta1, IL-23 and IL-17 in relation to the…
Descriptors: Rating Scales, Autism, Foreign Countries, Control Groups
