The threat of climate change makes it increasingly important for biologists and the public to understand how organisms respond to temperature. The Metabolic Theory of Ecology (MTE) predicts that temperature should affect organism performance, with implications for species interactions and ecosystems that span disciplines including mathematics,…

This dissertation is in two parts: Part 1 of the study focuses on investigating the feasibility of delivering turn-on rhodamine-based fluorophores through Glucose transporters (GLUTs) for biomedical applications, both "in vitro" and in vivo. Fluorescent GLUT targeting probes are essential for analyzing transport activity, monitoring…

While zinc (Zn[superscript 2+]) is a vital ion for cell function and human health, we are still learning about how Zn[superscript 2+] concentration and localization is regulated and the role that Zn[superscript 2+] fluctuations may play in regulating cell signaling and cell fate. Here, we use fluorescent tools to study the interaction between…

The professorate remains predominantly white, and predominantly male in 2023. Despite a perceived shift in educational practice towards the creation of inclusive climates and campus workplaces, Black women's career advancement to full professor over the past 25 years remained flat at a mere 2%. Black women's career advancement and well-being in…

This dissertation is presented in multiple article format with an introduction, a literature review, a design case, a mixed methods study, and a conclusion. The literature review outlines important concepts and theories that appear in subsequent manuscripts. The design case describes the seven-year design process that resulted in the online…

Metabolic Syndrome (MetS), a cluster of cardiometabolic abnormalities including elevated waist circumference, low high-density lipoprotein (HDL) cholesterol, high triglycerides, high blood pressure, and elevated fasting glucose, affects nearly 35% of American adults. The presence of MetS both predicts and contributes to the development of…

This case study investigated teachers' perceptions and experiences implementing heart rate (HR) monitors in high school physical education (PE) classes. Integrating technology, such as HR monitors, into the classroom influences the way teachers plan, instruct, assess, and motivate students in PE; however, successful integration is dependent upon…

The purpose of this study is to examine allostatic load and John Henryism within post-secondary science, technology, engineering, and mathematics (STEM) learning environments through identified cumulative traumatic stress. The physiological impact of prolonged stressors has deleterious health effects on historically minoritized students. The…

Background: First signs and symptoms of sepsis are difficult to diagnose and often missed. This quality improvement project was designed to improve care of adult cancer patients undergoing chemotherapy and biotherapy at a local ambulatory cancer treatment center who present with signs and symptoms of sepsis. The aim of this project was to improve…

This quantitative study was designed to investigate whether differences existed between body weight, body mass index, body fat percentage, and systolic blood pressure based on gender and ethnicity. Participants included 2,051 Delaware State University students enrolled in the Lifetime Fitness and Wellness course from January 2014 to December 2016.…

Transition metals play an important role in many biological processes, however, they are also toxic at high concentrations. Therefore, the uptake and efflux of these metals must be tightly regulated by the cell. Bacteria have evolved a variety of pathways and regulatory systems to monitor the presence and concentration of metals in the cellular…

The prevalence of diabetes mellitus (DM) is higher in American Indians/Alaska Natives (AI/AN) than in any other racial or ethnic group in the United States (U.S. Department of Health and Human Services [USDHHS] Centers for Disease Control and Prevention [CDC], 2018). In response to this escalating health issue, the U.S. government funded a number…

The purpose of this study was to explore the relationship between assessment of critical thinking as admission criteria as a predictor of success in the completion of an associate degree respiratory care program. The research site was a community college located in the southern United States. The sample included 176 students who completed Health…

Neurotransmitter:sodium symporter (NSS) proteins remove neurotransmitters released into the synapse through a transport process driven by the physiological sodium ion (Na[superscript +]) gradient. NSSs for dopamine, noradrenaline, and serotonin are targeted by the psychostimulants cocaine and amphetamines, as well as by antidepressants. The…

Bisphenol A (BPA) is a plastic monomer and plasticizer and is a chemical that has one of the highest volume production worldwide, with more than six billion pounds each year. Its primary use is the production of polycarbonate plastics, epoxy resins used to line metal cans in a host of plastic consumer products such as toys, water pipes, drinking…