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Direct linkAurora Callahan; Todd Smith – Biochemistry and Molecular Biology Education, 2025
A common exercise given to students early in a molecular biology course is the creation of a restriction map of a plasmid "digested" by two restriction enzymes (RE). Meanwhile, students have learned from an early age about the properties and analyses of circles in their mathematics courses. But it is rare for students to learn using…
Descriptors: Problem Solving, Puzzles, Molecular Biology, Assignments
Murphy Angelo; Yash Bhargava; Scott Takeo Aoki – Biochemistry and Molecular Biology Education, 2024
The complexity of RNA cannot be fully expressed with the canonical A, C, G, and U alphabet. To date, over 170 distinct chemical modifications to RNA have been discovered in living systems. RNA modifications can profoundly impact the cellular outcomes of messenger RNAs (mRNAs), transfer and ribosomal RNAs, and noncoding RNAs. Additionally, aberrant…
Descriptors: Genetics, Biochemistry, Molecular Biology, College Science
Download full textRoberto Reinoso-Tapia; Sara Galindo; Jaime Delgado-Iglesias; Javier Bobo-Pinilla – Journal of Turkish Science Education, 2024
The aim of this research was to evaluate and compare the efficiency of the flipped learning strategy with that of a conventional teaching method with respect to learning outcomes, cognitive gain, and perception and satisfaction with regard to the methodology used. The research was carried out during the 2021-2022 academic year and focused on a…
Descriptors: Blended Learning, Molecular Biology, Preservice Teachers, Academic Achievement
Naoto Shirasu; Shin'ichiro Yasunaga – Biochemistry and Molecular Biology Education, 2024
Here, we propose a laboratory exercise to quickly determine single nucleotide polymorphisms (SNPs) in human "alcohol dehydrogenase 1B (ADH1B)" and "aldehyde dehydrogenase 2 (ALDH2)" genes involved in alcohol metabolism. In this exercise, two different genotyping methods based on polymerase chain reaction (PCR), namely…
Descriptors: Genetics, Biochemistry, Students, Science Instruction
Tiantian Cheng; Lingzhen Cao; Meng Zou – American Biology Teacher, 2024
The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…
Descriptors: Biology, Genetics, Science Instruction, Physiology
Representing DNA for Machine Learning Algorithms: A Primer on One-Hot, Binary, and Integer Encodings
Yash Munnalal Gupta; Satwika Nindya Kirana; Somjit Homchan – Biochemistry and Molecular Biology Education, 2025
This short paper presents an educational approach to teaching three popular methods for encoding DNA sequences: one-hot encoding, binary encoding, and integer encoding. Aimed at bioinformatics and computational biology students, our learning intervention focuses on developing practical skills in implementing these essential techniques for…
Descriptors: Science Instruction, Teaching Methods, Genetics, Molecular Biology
Crystal Uminski; Dina L. Newman; L. Kate Wright – CBE - Life Sciences Education, 2025
Molecular biology can be challenging for undergraduate students because it requires visual literacy skills to interpret abstract representations of submicroscopic concepts, structures, and processes. The Conceptual-Reasoning-Mode framework suggests that visual literacy relies on applying conceptual knowledge to appropriately reason with the…
Descriptors: Visual Literacy, Student Attitudes, Molecular Biology, Genetics
Ludmila Tyler; Peter J. Kennelly; Shelly Engelman; Kirsten F. Block; Jennifer C. Bobenko; Jaclyn Catalano; Jesica A. Jones; Margaret I. Kanipes-Spinks; Yang Mooi Lim; Jennifer Loertscher; Tejiri Olafimihan; Hailey Reiss; Territa L. Upchurch-Poole; Yufeng Wei; Kimberly J. Linenberger Cortes; Victoria Del Gaizo Moore; Daniel R. Dries – Biochemistry and Molecular Biology Education, 2024
We present as a case study the evolution of a series of participant-centered workshops designed to meet a need in the life sciences education community--the incorporation of best practices in the assessment of student learning. Initially, the ICABL (Inclusive Community for the Assessment of Biochemistry and Molecular Biology/BMB Learning) project…
Descriptors: Science Education, Science Teachers, Teacher Workshops, Biological Sciences
Martina Blecic – Journal of Biological Education, 2024
In this paper I suggest a pragmatic model for the notion of 'information' used in molecular biology in the description of protein synthesis. Discarding any ontological commitments of the term 'information', I propose a view of information based on an analogy with communication. This view could at least supplement the existing information-metaphor…
Descriptors: Genetics, Molecular Biology, Figurative Language, Communication (Thought Transfer)
Shane Terrell Jinson Jr. – ProQuest LLC, 2024
Understanding the details of how scientific breakthroughs and discoveries emerge from prior work, knowledge, and collaboration is fundamental to science history. Traditional methods of collecting such relevant information and transforming it into rich narratives have existed since the inception of the scientific method. These typically involve…
Descriptors: Biological Sciences, Qualitative Research, Cytology, Authors
Leonie I. Johann; Fredrik K. H. Rusk; Michael J. Reiss; Jorge Groß – Journal of Biological Education, 2024
This study reports on the theoretical- and empirical-based design and evaluation of cell membrane biology learning activities within the Model of Educational Reconstruction and experiential realism. First, we designed analogy-based learning activities by considering students' and scientists' conceptions as described in the literature. Secondly, we…
Descriptors: Secondary School Students, Thinking Skills, Cytology, Molecular Biology
Risanti Dhaniaputri; Hadi Suwono; Betty Lukiati – Journal of Biological Education Indonesia (Jurnal Pendidikan Biologi Indonesia), 2024
Plant metabolite compounds have been applied on plant cellular metabolism, produces organic and inorganic compounds, primary and secondary bioactive molecules, such as glucose, amino acids, fat acids, alkaloids, flavonoids, and terpenoids. Undergraduate biology students learn about the plant terpenoid assisted by bioinformatics to store, manage,…
Descriptors: Foreign Countries, Science Instruction, Biology, Plants (Botany)
María Florencia Mosquillo; Gonzalo Scalese; Felipe Castro; Leticia Pérez-Díaz – Natural Sciences Education, 2024
An effective, practical approach for incorporating molecular biology tools to biology and biochemistry students is described. For 6 weeks, students are exposed to bacterial transformation, plasmid DNA purification and analysis, parasite transfection, ectopic expression of fluorescent proteins, fluorescence microscopy, and flow cytometry analysis.…
Descriptors: Active Learning, Student Projects, Science Education, Molecular Biology
R. A. Paggi; M. C. Ferrari; M. Cerletti; M. I. Giménez; T. S. Schwarz; A. Marchfelder; R. E. De Castro – Biochemistry and Molecular Biology Education, 2025
Perturbation of gene expression using RNA interference (RNAi) or CRISPR interference (CRISPRi) is a useful strategy to explore the function of essential genes. In the archaeon "Haloferax volcanii," the CRISPR-Cas system has been adapted as a CRISPRi tool to silence the expression of specific genes. We developed a laboratory class (LC) to…
Descriptors: Undergraduate Students, Laboratory Experiments, Science Instruction, Biochemistry
Rheanna E. Walther; Michael Hrabak; Douglas A. Bernstein – Journal of Microbiology & Biology Education, 2024
Molecular biology, broadly defined as the investigation of complex biomolecules in the laboratory, is a rapidly advancing field and as such the technologies available to investigators are constantly evolving. This constant advancement has obvious advantages because it allows students and researchers to perform more complex experiments in shorter…
Descriptors: Scientific Research, Molecular Biology, Science Laboratories, Genetics
