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Direct linkAurora Callahan; Todd Smith – Biochemistry and Molecular Biology Education, 2025
A common exercise given to students early in a molecular biology course is the creation of a restriction map of a plasmid "digested" by two restriction enzymes (RE). Meanwhile, students have learned from an early age about the properties and analyses of circles in their mathematics courses. But it is rare for students to learn using…
Descriptors: Problem Solving, Puzzles, Molecular Biology, Assignments
The Real Reason Why ATP Hydrolysis Is Spontaneous at pH > 7: It's (Mostly) the Proton Concentration!
Silverstein, Todd P. – Biochemistry and Molecular Biology Education, 2023
Common wisdom holds that ATP hydrolysis is spontaneous because of the weakness of its phosphoanhydride bonds, electrostatic repulsion within the polyanionic ATP[superscript 4]-molecule, and resonance stabilization of the inorganic phosphate and ADP products. By examining the pH-dependence of the hydrolysis Gibbs free energy, we show that in fact,…
Descriptors: Biochemistry, Molecular Biology, Science Education, Scientific Concepts
Murphy Angelo; Yash Bhargava; Scott Takeo Aoki – Biochemistry and Molecular Biology Education, 2024
The complexity of RNA cannot be fully expressed with the canonical A, C, G, and U alphabet. To date, over 170 distinct chemical modifications to RNA have been discovered in living systems. RNA modifications can profoundly impact the cellular outcomes of messenger RNAs (mRNAs), transfer and ribosomal RNAs, and noncoding RNAs. Additionally, aberrant…
Descriptors: Genetics, Biochemistry, Molecular Biology, College Science
Download full textRoberto Reinoso-Tapia; Sara Galindo; Jaime Delgado-Iglesias; Javier Bobo-Pinilla – Journal of Turkish Science Education, 2024
The aim of this research was to evaluate and compare the efficiency of the flipped learning strategy with that of a conventional teaching method with respect to learning outcomes, cognitive gain, and perception and satisfaction with regard to the methodology used. The research was carried out during the 2021-2022 academic year and focused on a…
Descriptors: Blended Learning, Molecular Biology, Preservice Teachers, Academic Achievement
Naoto Shirasu; Shin'ichiro Yasunaga – Biochemistry and Molecular Biology Education, 2024
Here, we propose a laboratory exercise to quickly determine single nucleotide polymorphisms (SNPs) in human "alcohol dehydrogenase 1B (ADH1B)" and "aldehyde dehydrogenase 2 (ALDH2)" genes involved in alcohol metabolism. In this exercise, two different genotyping methods based on polymerase chain reaction (PCR), namely…
Descriptors: Genetics, Biochemistry, Students, Science Instruction
Tiantian Cheng; Lingzhen Cao; Meng Zou – American Biology Teacher, 2024
The central dogma of molecular biology describes the transfer of genetic information from nucleic acids to proteins and stipulates that the system cannot work in the reverse direction. As a fundamental principle in biology, the dogma is as influential as it is controversial. Some commentators have debated the central dogma's empirical accuracy…
Descriptors: Biology, Genetics, Science Instruction, Physiology
Asmus, Stephen E.; Wells, Collin K.; Montalvo, Hanna M. – Biochemistry and Molecular Biology Education, 2023
Heart muscle cells, or cardiomyocytes, exhibit intrinsic contractility in vitro. We found that commercially-available mammalian cardiomyocytes serve as an excellent model system for studying the cytoskeleton and cellular contractility, fundamental topics in undergraduate cell and molecular biology courses. Embryonic rat cardiomyocytes were plated…
Descriptors: Anatomy, Cytology, Science Laboratories, Laboratory Equipment
Josep J. Centelles; Estefania Moreno; Pedro R. de Atauri – International Society for Technology, Education, and Science, 2023
Gamification is a very useful technique, that has been fully increasing in the last years. During the COVID-19 pandemic, our innovation teaching group sent to our students several games, that were used by them for self-studying. Considering that many numerical problems can be proposed in Biochemistry, rather than numerical games (sudoku, adding…
Descriptors: Gamification, Biochemistry, Vocabulary, Educational Games
D'Onofrio, María Guillermina; Rogers, Juan D. – Research Evaluation, 2022
The evaluation system is an important component of the institutional arrangements that may shape the career trajectories of researchers. Using logistic regression and recursive partition models, we analyze the resulting key individual level factors that seem to play an important role in the promotion of researchers through the research evaluation…
Descriptors: Research, Researchers, Foreign Countries, Molecular Biology
Craig, Paul A.; Nash, Jessica A.; Crawford, T. Daniel – Biochemistry and Molecular Biology Education, 2022
A programming workshop has been developed for biochemists and molecular biologists to introduce them to the power and flexibility of solving problems with Python. The workshop is designed to move users beyond a "plug-and-play" approach that is based on spreadsheets and web applications in their teaching and research to writing scripts to…
Descriptors: Programming Languages, Biochemistry, Molecular Biology, Data Analysis
Representing DNA for Machine Learning Algorithms: A Primer on One-Hot, Binary, and Integer Encodings
Yash Munnalal Gupta; Satwika Nindya Kirana; Somjit Homchan – Biochemistry and Molecular Biology Education, 2025
This short paper presents an educational approach to teaching three popular methods for encoding DNA sequences: one-hot encoding, binary encoding, and integer encoding. Aimed at bioinformatics and computational biology students, our learning intervention focuses on developing practical skills in implementing these essential techniques for…
Descriptors: Science Instruction, Teaching Methods, Genetics, Molecular Biology
Crystal Uminski; Dina L. Newman; L. Kate Wright – CBE - Life Sciences Education, 2025
Molecular biology can be challenging for undergraduate students because it requires visual literacy skills to interpret abstract representations of submicroscopic concepts, structures, and processes. The Conceptual-Reasoning-Mode framework suggests that visual literacy relies on applying conceptual knowledge to appropriately reason with the…
Descriptors: Visual Literacy, Student Attitudes, Molecular Biology, Genetics
Ludmila Tyler; Peter J. Kennelly; Shelly Engelman; Kirsten F. Block; Jennifer C. Bobenko; Jaclyn Catalano; Jesica A. Jones; Margaret I. Kanipes-Spinks; Yang Mooi Lim; Jennifer Loertscher; Tejiri Olafimihan; Hailey Reiss; Territa L. Upchurch-Poole; Yufeng Wei; Kimberly J. Linenberger Cortes; Victoria Del Gaizo Moore; Daniel R. Dries – Biochemistry and Molecular Biology Education, 2024
We present as a case study the evolution of a series of participant-centered workshops designed to meet a need in the life sciences education community--the incorporation of best practices in the assessment of student learning. Initially, the ICABL (Inclusive Community for the Assessment of Biochemistry and Molecular Biology/BMB Learning) project…
Descriptors: Science Education, Science Teachers, Teacher Workshops, Biological Sciences
Martina Blecic – Journal of Biological Education, 2024
In this paper I suggest a pragmatic model for the notion of 'information' used in molecular biology in the description of protein synthesis. Discarding any ontological commitments of the term 'information', I propose a view of information based on an analogy with communication. This view could at least supplement the existing information-metaphor…
Descriptors: Genetics, Molecular Biology, Figurative Language, Communication (Thought Transfer)
Shane Terrell Jinson Jr. – ProQuest LLC, 2024
Understanding the details of how scientific breakthroughs and discoveries emerge from prior work, knowledge, and collaboration is fundamental to science history. Traditional methods of collecting such relevant information and transforming it into rich narratives have existed since the inception of the scientific method. These typically involve…
Descriptors: Biological Sciences, Qualitative Research, Cytology, Authors
