Teaching chemistry and biology students about biologics design remains challenging despite its increasing importance in pharmaceutical development. Monoclonal antibodies, commonly called mAbs, are the most popular biologics. They have been developed into drugs to treat various diseases in the past decades. Multiple challenges exist for designing…

The scientists of the future will need to begin studying science to great depth, much earlier in life, in order to keep up with the accelerating pace of discovery and technological innovation. For this to be possible, engaging and child-friendly pedagogical approaches need to be developed that leverage the natural enthusiasm of young science…

The reported project-based laboratory unit introduces upper-division undergraduate students to the basics of computer-aided drug discovery as a part of a computational chemistry laboratory course. The students learn to perform model binding of organic molecules (ligands) to the DNA minor groove with computer-aided drug discovery (CADD) tools. The…

Molecular storytelling combines three-dimensional (3-D) structure visualization, chemical and biological knowledge, and multidisciplinary functional information from various bioinformatics data resources to generate new knowledge. It prepares students for independent and interdisciplinary learning, facile navigation of public databases to gather…

While structure-property relationships are commonly developed in applications of physical organic chemistry to real-world problems at the graduate level, they have not been generally emphasized in the undergraduate chemistry curriculum. For instance, the ability to modify the energy gap between the highest occupied molecular orbital (HOMO) and the…

We present an interactive discovery-based approach to studying the properties of real gases using simple, yet realistic, molecular dynamics software. Use of this approach opens up a variety of opportunities for students to interact with the behaviors and underlying theories of real gases. Students can visualize gas behavior under a variety of…