Heterocycles, more specifically those containing nitrogen, make up a family of molecules with great pharmaceutical potential. Many approved drugs, notably anticancer drugs, contain a nitrogen-based heterocycle. To expose students to this class of molecules, we used the Paal--Knorr reaction for the synthesis of edaravone, a pyrazolone derivative.…

Purpose: The study's primary aims were to describe the long-term speech outcomes for adolescents and young adults with a history of childhood apraxia of speech (CAS) and to examine the association of persistent speech sound errors with measures of literacy skills, phonological processing, motor speech production, and parent report of early motor…

Many autistic people and people with non-spectrum neurodevelopmental disabilities (e.g. intellectual disability) report feeling lonely, which can negatively impact their well-being. There is little longitudinal research, however, tracking changes in how autistic people experience, conceptualize, and cope with loneliness throughout their lives. A…

The impacts of the COVID-19 pandemic and the consequent social isolation can intensify some Parkinson's disease (PD) motor and non-motor symptoms. To minimize the damage to the physical and mental health of people with PD, strategies to promote health in this population must be adapted to the new reality. Considering the negative impact of social…

Maintaining healthy cognitive functioning and delaying cognitive decline in cognitively intact and cognitively impaired adults are major research initiatives for addressing dementia disease burden. Music interventions are promising, non-pharmaceutical treatment options for preserving cognitive function and psychological health in older adults with…

Background: Pragmatic communication difficulties encompass many distinct behaviours, including the use of vague and/or insufficient language, a common characteristic following traumatic brain injury (TBI) that negatively impacts psychosocial outcomes. Existing assessments evaluate pragmatic communication broadly, often with only one or two items…

Background: Concussion education is recommended to increase concussion knowledge, beliefs, and reporting intentions. The Concussion Awareness Training Tool for Youth (CATT-Youth) is a 40-minute e-Learning module developed for high school-aged youth. Aim: The aim of the study was to evaluate changes in concussion knowledge, beliefs, and reporting…

Background: Stroke has the highest global burden of any neurological disease. Many studies investigate secondary stroke prevention strategies, but the outcomes remain poor, and the rates of recurrent stroke stay high. Purpose: This review synthesizes the existing studies that focus on educational strategies for stroke survivors to reduce their…

Purpose: The prevalence of dysphagia in patients with neurodegenerative diseases (ND) is alarmingly high and frequently results in morbidity and accelerated mortality due to subsequent adverse events (e.g., aspiration pneumonia). Swallowing in patients with ND should be continuously monitored due to the progressive disease nature. Access to…

Background: Parkinson's disease (PD) leads to changes in verbal communications. The focus of most studies to date has been on speech impairment, which is specifically referred to as dysarthria. Although these studies are crucial to understanding the impact of PD on verbal communication, they do not focus on the features of dialogues between people…

This review addresses the question of a possible specificity of motor development of preterm children with no diagnosis of neurological impairment or major cerebral lesion. With that goal, we proceed with a narrative review on the basis of nine studies. All the studies used standardized assessments of motor abilities with a comparison methodology…

Background: Evidence should guide decisions in aphasia practice across the continuum of stroke care; however, evidence-practice gaps persist. This is particularly pertinent in the acute setting where 30% of people with stroke will have aphasia, and speech pathologists experience many challenges implementing evidence-based practice. This has…

In a bibliometric analysis, we used the PubMed search engine to count the number of publications identified by the search term "dissociative amnesia" for the years 2011--2020. We then counted publications from the same decade for five representative comparison disorders: "panic disorder," "anorexia nervosa,"…

Purpose: While dysarthria and dysphagia are known bulbar manifestations of amyotrophic lateral sclerosis (ALS), the relative prevalence of speech and swallowing impairments and whether these bulbar symptoms emerge at the same time point or progress at similar rates is not yet clear. We, therefore, sought to determine the relative prevalence of…

Purpose: The goal of this study was to identify some potential key cognitive and communicative processes underlying narrative discourse ability following traumatic brain injury (TBI). Specifically, this study (a) investigated the contribution of working memory (WM) and inferencing to narrative discourse comprehension and production; (b) tested key…