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Urgolites, Zhisen J.; Smith, Christine N.; Squire, Larry R. – Learning & Memory, 2015
Recent studies have asked whether activity in the medial temporal lobe (MTL) and the neocortex can distinguish true memory from false memory. A frequent complication has been that the confidence associated with correct memory judgments (true memory) is typically higher than the confidence associated with incorrect memory judgments (false memory).…
Descriptors: Memory, Cognitive Processes, Brain Hemisphere Functions, Accuracy
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Broadbent, Nicola J.; Gaskin, Stephane; Squire, Larry R.; Clark, Robert E. – Learning & Memory, 2010
In rodents, the novel object recognition task (NOR) has become a benchmark task for assessing recognition memory. Yet, despite its widespread use, a consensus has not developed about which brain structures are important for task performance. We assessed both the anterograde and retrograde effects of hippocampal lesions on performance in the NOR…
Descriptors: Surgery, Neurology, Recognition (Psychology), Novelty (Stimulus Dimension)
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Jessberger, Sebastian; Clark, Robert E.; Broadbent, Nicola J.; Clemenson, Gregory D., Jr.; Consiglio, Antonella; Lie, D. Chichung; Squire, Larry R.; Gage, Fred H. – Learning & Memory, 2009
New granule cells are born throughout life in the dentate gyrus of the hippocampal formation. Given the fundamental role of the hippocampus in processes underlying certain forms of learning and memory, it has been speculated that newborn granule cells contribute to cognition. However, previous strategies aiming to causally link newborn neurons…
Descriptors: Recognition (Psychology), Brain Hemisphere Functions, Animals, Role
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Squire, Larry R. – Science, 1986
Focuses on the brain processes and brain systems involved in learning and memory from a neuropsychological perspective of analysis. Reports findings related to the locus of memory storage, types of memory and knowledge, and memory consolidation. Models of animal memory are also examined. An extensive reference list is included. (ML)
Descriptors: Cognitive Processes, Encoding (Psychology), Human Body, Long Term Memory