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Connolly, John J.; Glessner, Joseph T.; Hakonarson, Hakon – Child Development, 2013
Efforts to understand the causes of autism spectrum disorders (ASDs) have been hampered by genetic complexity and heterogeneity among individuals. One strategy for reducing complexity is to target endophenotypes, simpler biologically based measures that may involve fewer genes and constitute a more homogenous sample. A genome-wide association…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Genetic Disorders
Winder, Breanna M.; Wozniak, Robert H.; Parladé, Meaghan V.; Iverson, Jana M. – Developmental Psychology, 2013
Communication spontaneously initiated by infants at heightened risk (HR; n = 15) for autism spectrum disorders (ASD) is compared with that in low-risk (LR; n = 15) infants at 13 and 18 months of age. Infants were observed longitudinally during naturalistic in-home interaction and semistructured play with caregivers. At both ages, HR infants…
Descriptors: Communication Skills, Infants, At Risk Persons, Autism