In the USA, Organic Chemistry I is a gateway course for undergraduate students seeking careers in medical- and health-related fields. Estimates of failure and withdrawal rates are approximately 40% at some large, public institutions and higher for specific segments of the student population, such as ethnic minorities, those of low socio-economic…

Research has demonstrated that academically successful students are effective, self-regulated learners. Moreover, exam wrapper interventions have been shown to foster the development of self-regulated learning behaviors on the part of college students. In this naturalistic, qualitative, and exploratory study, an exam wrapper intervention was…

This article describes a quasi-experimental study conducted in two Organic Chemistry I classrooms at a diverse, urban, public university. The treatment group received an exam wrapper intervention, a series of four written exercises administered throughout the semester designed to enhance students' academic self-regulation by promoting…

This column shares reflections or thoughtful opinions on issues of broad interest to the community. In this issue the authors describe how they discovered that by incorporating culturally relevant analogies and examples into our classrooms, it was possible to help students visualize the course material more effectively, while at the same time…

Organic Chemistry is perceived to be one of the most challenging of undergraduate science courses, and attrition from this course may impact decisions about pursuing a professional or academic career in the biomedical and related sciences. Research suggests that chemistry students who are strategic help seekers may outperform those students who…

This qualitative study investigated the achievement goal orientations of a group of all male pre-med students attending a small, urban undergraduate college. Semi-structured interviews examined under what circumstances students adopted extrinsic goals, mastery goals, or a mixture of the two. Findings indicated that while nearly all students…

The changes that have taken place in the organic chemistry laboratory course since 1980s are reviewed with reference to the quantity and diversity of discovery-based experiments available to date. The data illustrates that significant progress is towards accomplishing dramatic changes such as the almost universal adoption of microscale, the use of…

Conformational analysis of cyclohexanes is a fundamental, requisite topic covered in undergraduate organic chemistry. A molecular modeling experiment is designed with the view of extending students' boundaries of knowledge about cyclohexane conformational stabilities.

The molecular modeling was used to reinforce more general skills such as deducing and drawing reaction mechanisms, analyzing reaction kinetics and thermodynamics and drawing reaction coordinate energy diagrams. This modeling was done through the design of mechanistic puzzles, involving reactions not familiar to the students.