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Elizabeth Blank; Donald L. Gilbert; Steve W. Wu; Travis Larsh; Rana Elmaghraby; Rui Liu; Elizabeth Smith; Grace Westerkamp; Yanchen Liu; Paul S. Horn; Ethan Greenstein; John A. Sweeney; Craig A. Erickson; Ernest V. Pedapati – Journal of Autism and Developmental Disorders, 2025
Purpose: Major depressive disorder (MDD) disproportionately affects those living with autism spectrum disorder (ASD) and is associated with significant impairment and treatment recidivism. Methods: We studied the use of accelerated theta burst stimulation (ATBS) for the treatment of refractory MDD in ASD (3 treatments daily x 10 days). This…
Descriptors: Autism Spectrum Disorders, Depression (Psychology), Multiple Disabilities, Rating Scales
Mattos, Paulo; Rodrigues Louza, Mario; Fernandes Palmini, Andre Luis; de Oliveira, Irismar Reis; Lopes Rocha, Fabio – Journal of Attention Disorders, 2013
The available literature provides few studies on the effectiveness of methylphenidate in improving quality of life in individuals with ADHD. Objective: To assess the effectiveness of Methyphenidate OROS formulation (OROS MPH) through QoL in adults with ADHD. Method: A 12-week, multicenter, open-label trial involving 60 patients was used. The…
Descriptors: Quality of Life, Drug Therapy, Attention Deficit Hyperactivity Disorder, Outcomes of Treatment
Spates, C. Richard; Kalata, Alyssa H.; Ozeki, Satoshi; Stanton, Cory E.; Peters, Sofia – Behavior Modification, 2013
This article presents preliminary findings from use of a novel computer program that implements an evidence-based psychological intervention to treat depression based on behavioral activation (BA) therapy. The program is titled “Building a Meaningful Life Through Behavioral Activation”. The findings derive from an open trial with moderate to…
Descriptors: Therapy, Behavior Modification, Computer Software, Depression (Psychology)
Bombardier, Charles H.; Ehde, Dawn M.; Gibbons, Laura E.; Wadhwani, Roini; Sullivan, Mark D.; Rosenberg, Dori E.; Kraft, George H. – Journal of Consulting and Clinical Psychology, 2013
Objective: Physical activity represents a promising treatment for major depressive disorder (MDD) in people with multiple sclerosis (MS). We conducted a single-blind, two-arm randomized controlled trial comparing a 12-week physical activity counseling intervention delivered primarily by telephone (n = 44) to a wait-list control group (N = 48).…
Descriptors: Rating Scales, Physical Activities, Intervention, Mental Disorders
Bieling, Peter J.; Hawley, Lance L.; Bloch, Richard T.; Corcoran, Kathleen M.; Levitan, Robert D.; Young, L. Trevor; MacQueen, Glenda M.; Segal, Zindel V. – Journal of Consulting and Clinical Psychology, 2012
Objective: To examine whether metacognitive psychological skills, acquired in mindfulness-based cognitive therapy (MBCT), are also present in patients receiving medication treatments for prevention of depressive relapse and whether these skills mediate MBCT's effectiveness. Method: This study, embedded within a randomized efficacy trial of MBCT,…
Descriptors: Prevention, Program Effectiveness, Rating Scales, Personality Traits
Harkness, Kate L.; Bagby, R. Michael; Kennedy, Sidney H. – Journal of Consulting and Clinical Psychology, 2012
Objective: A substantial number of patients with major depressive disorder (MDD) do not respond to treatment, and recurrence rates remain high. The purpose of this study was to examine a history of severe childhood abuse as a moderator of response following a 16-week acute treatment trial, and of recurrence over a 12-month follow-up. Method:…
Descriptors: Outcomes of Treatment, Rating Scales, Children, Antisocial Behavior
Siddique, Juned; Chung, Joyce Y.; Brown, C. Hendricks; Miranda, Jeanne – Journal of Consulting and Clinical Psychology, 2012
Objective: To examine whether there are latent trajectory classes in response to treatment and whether they moderate the effects of medication versus psychotherapy. Method: Data come from a 1-year randomized controlled trial of 267 low-income, young (M = 29 years), minority (44% Black, 50% Latina, 6% White) women with current major depression…
Descriptors: Females, Health Services, Rating Scales, Anxiety
Dobkin, Roseanne D.; Rubino, Jade Tiu; Allen, Lesley A.; Friedman, Jill; Gara, Michael A.; Mark, Margery H.; Menza, Matthew – Journal of Consulting and Clinical Psychology, 2012
Objective: The purpose of this study was to examine predictors of treatment response to cognitive-behavioral therapy (CBT) for depression in Parkinson's disease (PD). Method: The sample comprised 80 depressed ("DSM-IV" criteria) adults with PD (60% male) and their caregivers who participated in an National Institutes of Health-sponsored…
Descriptors: Rating Scales, Therapy, Diseases, Depression (Psychology)
Stulz, Niklaus; Thase, Michael E.; Klein, Daniel N.; Manber, Rachel; Crits-Christoph, Paul – Journal of Consulting and Clinical Psychology, 2010
Objective: Psychotherapy-pharmacotherapy combinations are frequently recommended for the treatment of chronic depressive disorders. Our aim in this novel reanalysis of archival data was to identify patient subgroups on the basis of symptom trajectories and examine the clinical significance of the resultant classification on basis of differential…
Descriptors: Behavioral Science Research, Rating Scales, Patients, Severity (of Disability)
Brothers, Brittany M.; Yang, Hae-Chung; Strunk, Daniel R.; Andersen, Barbara L. – Journal of Consulting and Clinical Psychology, 2011
Objective: In this Phase II trial, we evaluated a novel psychological treatment for depressed patients coping with the stresses of cancer. Effectiveness of a combined biobehavioral intervention (BBI) and cognitive behavior therapy (CBT) was studied. Method: Participants were 36 cancer survivors (mean age = 49 years; 88% Caucasian; 92% female)…
Descriptors: Anxiety, Fatigue (Biology), Intervention, Quality of Life
Adler, Lenard A.; Spencer, Thomas J.; Williams, David W.; Moore, Rodney J.; Michelson, David – Journal of Attention Disorders, 2008
Objective: Previously, data from 97 weeks of open-label atomoxetine treatment of adults with attention-deficit/hyperactivity disorder (ADHD) were reported. This final report of that study presents results from over 4 years of treatment. Method: Results were derived from the study of 384 patients (125 patients remaining in the open-label trial…
Descriptors: Safety, Attention Deficit Hyperactivity Disorder, Rating Scales, Patients
Manber, Rachel; Kraemer, Helena C.; Arnow, Bruce A.; Trivedi, Madhukar H.; Rush, A. John; Thase, Michael E.; Rothbaum, Barbara O.; Klein, Daniel N.; Kocsis, James H.; Gelenberg, Alan J.; Keller, Martin E. – Journal of Consulting and Clinical Psychology, 2008
The main aim of the present novel reanalysis of archival data was to compare the time to remission during 12 weeks of treatment of chronic depression following antidepressant medication (n = 218), psychotherapy (n = 216), and their combination (n = 222). Cox regression survival analyses revealed that the combination of medication and psychotherapy…
Descriptors: Rating Scales, Psychotherapy, Depression (Psychology), Anxiety
Minami, Takuya; Wampold, Bruce E.; Serlin, Ronald C.; Kircher, John C.; Brown, George S. – Journal of Consulting and Clinical Psychology, 2007
This study estimates pretreatment-posttreatment effect size benchmarks for the treatment of major depression in adults that may be useful in evaluating psychotherapy effectiveness in clinical practice. Treatment efficacy benchmarks for major depression were derived for 3 different types of outcome measures: the Hamilton Rating Scale for Depression…
Descriptors: Psychotherapy, Rating Scales, Effect Size, Depression (Psychology)
Foster, Cynthia Ewell; Webster, Melissa C.; Weissman, Myrna M.; Pilowsky, Daniel J.; Wickramaratne, Priya J.; Talati, Ardesheer; Rush, A. John; Hughes, Carroll W.; Garber, Judy; Malloy, Erin; Cerda, Gabrielle; Kornstein, Susan G.; Alpert, Jonathan E.; Wisniewski, Stephen R.; Trivedi, Madhukar H.; Fava, Maurizio; King, Cheryl A. – Journal of Clinical Child and Adolescent Psychology, 2008
Family functioning and parenting were hypothesized to mediate the relation between remission of maternal depression and children's psychosocial adjustment. Participants were 114 mother-child dyads participating in the Sequenced Treatment Alternatives to Relieve Depression Child 3-month follow-up. All mothers had been diagnosed with major…
Descriptors: Mothers, Depression (Psychology), Parent Influence, Adjustment (to Environment)
Hopko, D. R.; Robertson, S. M. C.; Colman, L. – International Journal of Behavioral Consultation and Therapy, 2008
In recent years there has been increased focus on evaluating the efficacy of psychosocial interventions for cancer patients. Among the several limitations inherent to these programs of research, few studies have targeted patients with well-diagnosed clinical depression and little is known about factors that best predict treatment outcome and…
Descriptors: Marital Status, Cancer, Patients, Depression (Psychology)
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