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Direct linkChez, Michael; Kile, Shawn; Lepage, Christopher; Parise, Carol; Benabides, Bobbie; Hankins, Andrea – Journal of Autism and Developmental Disorders, 2020
Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…
Descriptors: Outcomes of Treatment, Randomized Controlled Trials, Pilot Projects, Drug Therapy
Taylor, Briana J.; Sanders, Kevin B.; Kyle, Marie; Pedersen, Kahsi A.; Veenstra-Vanderweele, Jeremy; Siegel, Matthew – Journal of Autism and Developmental Disorders, 2019
Psychiatric hospitalization of children with autism spectrum disorder (ASD) is common, but there is little comparative information available on different psychiatric hospital treatment models. Children with ASD ages 4-20 were enrolled upon admission to either a specialized (N = 53) or a general child psychiatric unit (N = 27). Caregivers completed…
Descriptors: Psychiatric Hospitals, Patients, Children, Adolescents
Sannar, Elise M.; Palka, Tamara; Beresford, Carol; Peura, Christine; Kaplan, Desmond; Verdi, Mary; Siegel, Matthew; Kaplan, Shir; Grados, Marco – Journal of Autism and Developmental Disorders, 2018
We examined the relationship between sleep duration and awakenings to Aberrant Behavior Checklist-Community (ABC-C) and Autism Diagnostic Observation Schedule (ADOS-2) scores in hospitalized youth with ASD and behavioral disturbance. Participants included 106 patients with a stay of at least 10 nights. Sleep in the hospital was recorded by staff…
Descriptors: Sleep, Correlation, Behavior Problems, Severity (of Disability)
Storch, Eric A.; Jones, Anna M.; Lack, Caleb W.; Ale, Chelsea M.; Sulkowski, Michael L.; Lewin, Adam B.; De Nadai, Alessandro S.; Murphy, Tanya K. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Rage attacks have been documented in youth with varied psychiatric disorders, but few data have been reported on the clinical characteristics and correlates of rage attacks among children with obsessive-compulsive disorder (OCD). Method: Participants were 86 children (ages 6-16 years) with a primary diagnosis of OCD. Patients and their…
Descriptors: Anxiety Disorders, Patients, Measures (Individuals), Severity (of Disability)
Akhondzadeh, Shahin; Tajdar, Hamid; Mohammadi, Mohammad-Reza; Mohammadi, Mohammad; Nouroozinejad, Gholam-Hossein; Shabstari, Omid L.; Ghelichnia, Hossein-Ali – Child Psychiatry and Human Development, 2008
It has been reported that autism is a hypoglutamatergic disorder. Therefore, it was of interest to assess the efficacy of piracetam, a positive modulator of AMPA-sensitive glutamate receptors in autistic disorder. About 40 children between the ages three and 11 years (inclusive) with a DSM IV clinical diagnosis of autism and who were outpatients…
Descriptors: Autism, Children, Patients, Drug Therapy
Handen, Benjamin L.; Hardan, Antonio Y. – Journal of the American Academy of Child & Adolescent Psychiatry, 2006
Objective: Olanzapine, an atypical antipsychotic, has been shown to be efficacious for treatment of psychotic and mood disorders in adults. This prospective, open-label study was conducted to examine the safety and usefulness of olanzapine in treating disruptive behavior disorders in adolescents with subaverage intelligence. Method: Sixteen…
Descriptors: Check Lists, Intelligence, Safety, Moderate Mental Retardation
