This study aiming to compare the effectiveness of Cognitive Orientation to Daily Occupational Performance (CO-OP) and Conductive Education (CE) approaches on motor skills, activity limitation and participation restrictions in children with Down Syndrome (DS). Twelve children were randomly assigned into two groups. Twelve-week CO-OP or CE…

The validity and reliability of the Test of Gross Motor Development-3 (TGMD-3) were measured, taking into consideration the preference for visual learning of children with autism spectrum disorder (ASD). The TGMD-3 was administered to 14 children with ASD (4-10 years) and 21 age-matched typically developing children under two conditions: TGMD-3…

We performed cerebellum segmentation and parcellation on magnetic resonance images from right-handed boys, aged 6-13 years, including 22 boys with autism [16 with language impairment (ALI)], 9 boys with Specific Language Impairment (SLI), and 11 normal controls. Language-impaired groups had reversed asymmetry relative to unimpaired groups in…

This prospective study of 17 high-functioning residentially treated adolescents with autism found that cognitive shifting, as measured by card sorting tests, was the only significant factor in predicting progress in social understanding. (Author/JDD)

Twenty-eight children (ages 5-13) with mental retardation, hyperactivity, and inattentiveness were administered fenfluramine and methylphenidate. Fenfluramine was superior to placebo on the memory task, whereas methylphenidate reduced commission errors on a continuous performance test. Methylphenidate caused shorter response times whereas…

Twenty-six children (ages 5-12) with attention deficit hyperactivity disorder were tested before and after treatment with methylphenidate. Few performance tests predicted clinical response to medication. Chronological age and performance on a memory distraction task and the Graduated Holes Task were moderately correlated with clinical outcome.…

Intelligence quotient profiles in 81 high-functioning children and adults with autism were examined. Profiles did not reveal the presumed typical pattern of a lower verbal IQ than performance IQ. Results found that individuals with autism demonstrated a wide range of ability levels and patterns on the Wechsler Intelligence Scales, without a single…

Scores from the Vineland Adaptive Behavior Scale were compared to age and performance IQ for 72 children and adolescents with autism and 37 nonautistic controls with mental retardation. The relationship between the two groups' adaptive behavior profiles was stable from preschool age through adolescence. Increasing IQ was associated with lower…