Background: The differential susceptibility hypothesis states that some genetic variants that confer risk in adverse environments are beneficial in normal or nurturing environments. The cholinergic system is promising as a source of susceptibility genes because of its involvement in learning and neural plasticity. The cholinergic receptor gene…

Personality traits may be viable candidates for mediators of the relationship between genetic risk and ADHD. Participants were 578 children (331 boys; 320 children with ADHD) between the ages of six and 18. Parents and teachers completed a comprehensive, multi-stage diagnostic procedure to assess ADHD and comorbid disorders. Mother completed the…

The revised Temperament and Character Inventory (TCI-R) is the third stage of development of a widely used multiscale personality inventory that began with the Tridimensional Personality Questionnaire (TPQ) and then the Temperament and Character Inventory (TCI). The author describes the third stage of the psychobiological theory of temperament and…

Medical and psychological evaluations and dermatoglyphic analysis of 4 XYY infants followed for 2 1/2 to 3 1/2 years are presented in case history format. (KW)

Objective: To compare the pattern of familial aggregation of psychopathology in children who are good responders (GR) to methylphenidate (MPH) versus those who are poor responders (PR). Method: A total of 118 clinically referred children ages 6 to 12 years, diagnosed with ADHD participated in a double-blind, placebo-controlled, randomized 2-week…

The concept and measurement of psychopathy in young people is discussed with respect to five key issues: (1) the respective merits of self-reports and ratings by others; (2) whether callous/unemotional (CU) features may be more appropriately tapped by physiological measures; (3) the possible utility of genetic studies; (4) the distinctiveness of…

Objective: To estimate the genetic and environmental contributions to oppositional defiant behavior (ODB) from mother, father, and teacher report using the Conners Revised Short Forms in a large twin sample. Method: ODB data were collected from 1,595 mothers, 1,114 fathers, and 793 teachers of 7-year-old twin pairs from the Netherlands Twin…

Experiences in prenatal life and early childhood that may cause personality disorders or criminal behavior in later life are examined in these proceedings of the Subcommittee on Childhood Experiences as Causes of Criminal Behavior, of the Standing Committee on Health, Welfare and Science, Senate of Canada. This issue, the fifth in a series of 19…

Experiences in prenatal life and early childhood that may cause personality disorders or criminal behavior in later life are examined in these proceedings of the Subcommittee on Childhood Experiences as Causes of Criminal Behavior, of the Standing Committee on Health, Welfare and Science, Senate of Canada. This issue, the sixth in a series of 19…

Experiences in prenatal life and early childhood that may cause personality disorders or criminal behavior in later life are examined in these proceedings of the Subcommittee on Childhood Experiences as Causes of Criminal Behavior of the Standing Committee on Health, Welfare and Science. This issue, the tenth in a series of 19 hearings dating from…

Experiences in prenatal life and early childhood that may cause personality disorders or criminal behavior in later life are examined in these proceedings of the Subcommittee on Childhood Experiences as Causes of Criminal Behavior of the Standing Committee on Health, Welfare and Science. This issue, the first in a series of 19 hearings dating from…

Experiences in prenatal life and early childhood that may cause personality disorders or criminal behavior in later life are examined in these proceedings of the subcommittee on Childhood Experiences as Cause of Criminal Behavior of the Standing Committee on Health, Welfare and Science. This issue, the second in a series of 19 hearings dating from…