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Direct linkRankin, James A.; Tomeny, Theodore S. – Journal of Autism and Developmental Disorders, 2019
Research on siblings of youth with autism spectrum disorder (ASD) suggests that some phenotypic presentation, known as the broader autism phenotype (BAP), is common among siblings without an ASD diagnosis (e.g., Ruzich et al. in Autism Res 9(6):658-665, 2016). Whereas the symptoms that underlie both ASD and the BAP share commonality, the structure…
Descriptors: Autism, Pervasive Developmental Disorders, Clinical Diagnosis, Genetics
Wan, Ming Wai; Green, Jonathan; Scott, Jordan – Autism: The International Journal of Research and Practice, 2019
Social communicative precursors to autism spectrum disorder may influence how infants who are later diagnosed with autism spectrum disorder interact with their social partners and the responses they receive, thus bidirectionally influencing early social experience. This systematic review aimed to identify a developmental timeline for parent-infant…
Descriptors: Autism, Pervasive Developmental Disorders, Infants, At Risk Persons
Raza, Sarah; Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Journal of Autism and Developmental Disorders, 2020
Social-emotional behavior in autism spectrum disorder (ASD) was examined among high-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers. Caregivers completed the Infant-Toddler Social Emotional Assessment (ITSEA) at 18 months, and blind diagnostic assessment for ASD was conducted at 36 months.…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Clinical Diagnosis
Swanson, Meghan R.; Shen, Mark D.; Wolff, Jason J.; Boyd, Brian; Clements, Mark; Rehg, James; Elison, Jed T.; Paterson, Sarah; Parish-Morris, Julia; Chappell, J. Chad; Hazlett, Heather C.; Emerson, Robert W.; Botteron, Kelly; Pandey, Juhi; Schultz, Robert T.; Dager, Stephen R.; Zwaigenbaum, Lonnie; Estes, Annette M.; Piven, Joseph – Child Development, 2018
Children's early language environments are related to later development. Little is known about this association in siblings of children with autism spectrum disorder (ASD), who often experience language delays or have ASD. Fifty-nine 9-month-old infants at high or low familial risk for ASD contributed full-day in-home language recordings.…
Descriptors: Infants, Autism, Pervasive Developmental Disorders, Environmental Influences
Campbell, Susan B.; Northrup, Jessie B.; Tavares, Amy B. – Autism: The International Journal of Research and Practice, 2019
Children with autism spectrum disorder often demonstrate difficulties with self-regulation, although studies of this construct in young children with autism spectrum disorder are limited. In this study, developmental changes were examined using a measure of self-regulation appropriate for young children, resistance to temptation. At 22, 28, and 34…
Descriptors: Toddlers, Risk, Genetics, Autism
Hilton, Claudia L.; Babb-Keeble, Alison; Westover, Erin Eitzmann; Zhang, Yi; Adams, Claire; Collins, Diane M.; Karmarkar, Amol; Reistetter, Timothy A.; Constantino, John N. – Journal of Autism and Developmental Disorders, 2016
This study examined sensory responsiveness in unaffected siblings of children with autism spectrum disorder (ASD) and associations between sensory responsiveness and social severity. Sensory Profile Caregiver Questionnaires and Social Responsiveness Scales were completed by parents of 185 children between age 4 and 10.95 years. Significant…
Descriptors: Autism, Pervasive Developmental Disorders, Sensory Integration, Responses
Roberts, Jane E.; Tonnsen, Bridgette L.; McCary, Lindsay M.; Caravella, Kelly E.; Shinkareva, Svetlana V. – Journal of Autism and Developmental Disorders, 2016
Fragile X syndrome (FXS) is the most common known genetic cause of autism spectrum disorder (ASD). Although 50-75% of children with FXS meet ASD criteria, no studies have compared ASD symptoms in infants with FXS versus other high risk groups, such as siblings of children with ASD (ASIBs). Using the Autism Observation Scale for Infants, our…
Descriptors: Genetic Disorders, Intellectual Disability, Congenital Impairments, Infants
Oerlemans, Anoek M.; Hartman, Catharina A.; De Bruijn, Yvette G. E.; Van Steijn, Daphne J.; Franke, Barbara; Buitelaar, Jan K.; Rommelse, Nanda N. J. – Journal of Autism and Developmental Disorders, 2015
Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are highly heterogeneous neuropsychiatric disorders, that frequently co-occur. This study examined whether stratification into single-incidence (SPX) and multi-incidence (MPX) is helpful in (a) parsing heterogeneity and (b) detecting overlapping and unique…
Descriptors: Autism, Pervasive Developmental Disorders, Attention Deficit Hyperactivity Disorder, Genetics
Concern for Another's Distress in Toddlers at High and Low Genetic Risk for Autism Spectrum Disorder
Campbell, Susan B.; Leezenbaum, Nina B.; Schmidt, Emily N.; Day, Taylor N.; Brownell, Celia A. – Journal of Autism and Developmental Disorders, 2015
We examined concern for others in 22-month-old toddlers with an older sibling with autism spectrum disorder (ASD) and low risk typically-developing toddlers with older siblings. Responses to a crying infant and an adult social partner who pretended to hurt her finger were coded. Children with a later diagnosis of ASD showed limited empathic…
Descriptors: Autism, Pervasive Developmental Disorders, Toddlers, Sibling Relationship
Oerlemans, Anoek M.; Hartman, Catharina A.; Franke, Barbara; Buitelaar, Jan K.; Rommelse, Nanda N. J. – Journal of Autism and Developmental Disorders, 2016
Children with an autism spectrum disorder (ASD) and their unaffected siblings from 54 simplex (SPX, one individual in the family affected) and 59 multiplex (MPX, two or more individuals affected) families, and 124 controls were assessed on intelligence, social cognition and executive functions. SPX and MPX ASD probands displayed similar cognitive…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Siblings
Hogan, Abigail L.; Caravella, Kelly E.; Ezell, Jordan; Rague, Lisa; Hills, Kimberly; Roberts, Jane E. – Journal of Autism and Developmental Disorders, 2017
No studies to date have prospectively examined early autism spectrum disorder (ASD) markers in infants with fragile X syndrome (FXS), who are at elevated risk for ASD. This paper describes the developmental profiles of eight infants with FXS from 9 to 24 months of age. Four meet diagnostic criteria for ASD at 24 months of age, and four do not.…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Infants
Tsai, Hsiao-Wei Joy; Cebula, Katie; Fletcher-Watson, Sue – Journal of Autism and Developmental Disorders, 2017
The influence of the broader autism phenotype (BAP) on the adjustment of siblings of children with autism has previously been researched mainly in Western cultures. The present research evaluated a diathesis-stress model of sibling adjustment using a questionnaire study including 80 and 75 mother-typically developing sibling dyads in Taiwan and…
Descriptors: Foreign Countries, Autism, Pervasive Developmental Disorders, Genetics
Thomas, Michael S. C.; Davis, Rachael; Karmiloff-Smith, Annette; Knowland, Victoria C. P.; Charman, Tony – Developmental Science, 2016
This article outlines the "over-pruning hypothesis" of autism. The hypothesis originates in a neurocomputational model of the regressive sub-type (Thomas, Knowland & Karmiloff-Smith, 2011a, 2011b). Here we develop a more general version of the over-pruning hypothesis to address heterogeneity in the timing of manifestation of ASD,…
Descriptors: Autism, Pervasive Developmental Disorders, Computer Simulation, Symptoms (Individual Disorders)
Campbell, Susan B.; Leezenbaum, Nina B.; Mahoney, Amanda S.; Day, Taylor N.; Schmidt, Emily N. – Autism: The International Journal of Research and Practice, 2015
Infant siblings of children with an autism spectrum disorder are at heightened genetic risk to develop autism spectrum disorder. We observed high risk (n?=?35) and low risk (n?=?27) infants at 11?months during free play with a parent. Children were assessed for autism spectrum disorder in toddlerhood. High-risk infants with a later diagnosis…
Descriptors: Autism, Pervasive Developmental Disorders, Infants, Siblings
Dimian, Adele F.; Botteron, Kelly N.; Dager, Stephen R.; Elison, Jed T.; Estes, Annette M.; Pruett, John R., Jr.; Schultz, Robert T.; Zwaigenbaum, Lonnie; Piven, Joseph; Wolff, Jason J. – Journal of Autism and Developmental Disorders, 2017
Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose…
Descriptors: Risk, Self Destructive Behavior, Autism, Pervasive Developmental Disorders
