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Direct linkHu, Valerie W. – Child Development, 2013
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that affect an estimated 1 in 110 individuals. Although there is a strong genetic component associated with these disorders, this review focuses on the multifactorial nature of ASD and how different genome-wide (genomic) approaches contribute to our understanding of autism.…
Descriptors: Genetics, Pervasive Developmental Disorders, Autism, Children
Gurkan, C. Kagan; Hagerman, Randi J. – Research in Autism Spectrum Disorders, 2012
Autism is a neurodevelopmental disorder consisting of a constellation of symptoms that sometimes occur as part of a complex disorder characterized by impairments in social interaction, communication and behavioral domains. It is a highly disabling disorder and there is a need for treatment targeting the core symptoms. Although autism is accepted…
Descriptors: Genetic Disorders, Autism, Asperger Syndrome, Genetics
Glatt, Stephen J.; Tsuang, Ming T.; Winn, Mary; Chandler, Sharon D.; Collins, Melanie; Lopez, Linda; Weinfeld, Melanie; Carter, Cindy; Schork, Nicholas; Pierce, Karen; Courchesne, Eric – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Autism spectrum disorders (ASDs) are highly heritable neurodevelopmental disorders that onset clinically during the first years of life. ASD risk biomarkers expressed early in life could significantly impact diagnosis and treatment, but no transcriptome-wide biomarker classifiers derived from fresh blood samples from children with…
Descriptors: Delayed Speech, Autism, Toddlers, Infants
Thapar, Anita; Cooper, Miriam; Eyre, Olga; Langley, Kate – Journal of Child Psychology and Psychiatry, 2013
Background: Attention deficit hyperactivity disorder (ADHD) and its possible causes still attract controversy. Genes, pre and perinatal risks, psychosocial factors and environmental toxins have all been considered as potential risk factors. Method: This review (focussing on literature published since 1997, selected from a search of PubMed)…
Descriptors: Psychopathology, Risk, Public Health, Diagnostic Tests
Caglayan, Ahmet O. – Developmental Medicine & Child Neurology, 2010
Aims: Over the past decade, genetic tests have become available for numerous heritable disorders, especially those whose inheritance follows the Mendelian model. Autism spectrum disorders (ASDs) represent a group of developmental disorders with a strong genetic basis. During the past few years, genetic research in ASDs has been successful in…
Descriptors: Autism, Testing, Genetics, Therapy
Smith, Shelley D. – Mental Retardation and Developmental Disabilities Research Reviews, 2007
Genetic factors are important contributors to language and learning disorders, and discovery of the underlying genes can help delineate the basic neurological pathways that are involved. This information, in turn, can help define disorders and their perceptual and processing deficits. Initial molecular genetic studies of dyslexia, for example,…
Descriptors: Pervasive Developmental Disorders, Dyslexia, Attention Deficit Disorders, Genetics
Haines, Jonathan; Camarata, Stephen – Mental Retardation and Developmental Disabilities Research Reviews, 2004
The purpose of this review is to provide a model for studying genetic association of response to intervention in child language disorders. In addition to a theoretical overview and review of different approaches to studying candidate genes, a specific methodology for completing this type of analysis is presented. The goal of the analysis is to…
Descriptors: Language Impairments, Child Language, Genetics, Outcomes of Treatment
