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Classifying Autism Spectrum Disorders by ADI-R: Subtypes or Severity Gradient?
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Cholemkery, Hannah; Medda, Juliane; Lempp, Thomas; Freitag, Christine M. – Journal of Autism and Developmental Disorders, 2016
To reduce phenotypic heterogeneity of Autism spectrum disorders (ASD) and add to the current diagnostic discussion this study aimed at identifying clinically meaningful ASD subgroups. Cluster analyses were used to describe empirically derived groups based on the Autism Diagnostic Interview-revised (ADI-R) in a large sample of n = 463 individuals…
Descriptors: Autism, Pervasive Developmental Disorders, Multivariate Analysis, Children
Detecting Subgroups in Children Diagnosed with Pervasive Developmental Disorder--Not Otherwise Specified
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Brennan, Laura; Barton, Marianne; Chen, Chi-Ming; Green, James; Fein, Deborah – Journal of Autism and Developmental Disorders, 2015
Hierarchical cluster analyses were used to detect three subgroups in a sample of children with pervasive developmental disorder--not otherwise specified (PDD-NOS) evaluated at ages 2 and 4. At age 2, Cluster 1 demonstrated few autism symptoms and high cognitive scores; 60% no longer met criteria for PDD at 4. Cluster 2 exhibited more autism…
Descriptors: Clinical Diagnosis, Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders)