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Direct linkMerker, Sören; Reif, Andreas; Ziegler, Georg C.; Weber, Heike; Mayer, Ute; Ehlis, Ann-Christine; Conzelmann, Annette; Johansson, Stefan; Müller-Reible, Clemens; Nanda, Indrajit; Haaf, Thomas; Ullmann, Reinhard; Romanos, Marcel; Fallgatter, Andreas J.; Pauli, Paul; Strekalova, Tatyana; Jansch, Charline; Vasquez, Alejandro Arias; Haavik, Jan; Ribasés, Marta; Ramos-Quiroga, Josep Antoni; Buitelaar, Jan K.; Franke, Barbara; Lesch, Klaus-Peter – Journal of Child Psychology and Psychiatry, 2017
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental disorder with profound cognitive, behavioral, and psychosocial impairments with persistence across the life cycle. Our initial genome-wide screening approach for copy number variants (CNVs) in ADHD implicated a duplication of…
Descriptors: Attention Deficit Hyperactivity Disorder, Neurological Impairments, Genetic Disorders, Physiology
Barona, Manuela; Taborelli, Emma; Corfield, Freya; Pawlby, Susan; Easter, Abigail; Schmidt, Ulrike; Treasure, Janet; Micali, Nadia – Journal of Child Psychology and Psychiatry, 2017
Introduction: Although recent research has focused on the effects of maternal eating disorders (EDs) on children, little is known about the effect of maternal EDs on neurobiological outcomes in newborns and infants. This study is the first to investigate neurobehavioural regulation and cognitive development in newborns and infants of mothers with…
Descriptors: Cognitive Development, Mothers, Control Groups, Eating Disorders
Karatoreos, Ilia N.; McEwen, Bruce S. – Journal of Child Psychology and Psychiatry, 2013
Background: Adaptation is key to survival. An organism must adapt to environmental challenges in order to be able to thrive in the environment in which they find themselves. Resilience can be thought of as a measure of the ability of an organism to adapt, and to withstand challenges to its stability. In higher animals, the brain is a key player in…
Descriptors: Physiology, Neurology, Biology, Resilience (Psychology)
Mills, Natalie T.; Scott, James G.; Wray, Naomi R.; Cohen-Woods, Sarah; Baune, Bernhard T. – Journal of Child Psychology and Psychiatry, 2013
Background: While cytokines have been implicated in the pathophysiology of depression in adults, the potential role in younger age groups such as adolescents is less clear. This article therefore reviews the literature (a) to explore the relationship between cytokines and depression in adolescents, and (b) to examine how cytokines may be related…
Descriptors: Role, Depression (Psychology), Pathology, Physiology
Monk, Catherine; Georgieff, Michael K.; Osterholm, Erin A. – Journal of Child Psychology and Psychiatry, 2013
Background: Accumulating data from animal and human studies indicate that the prenatal environment plays a significant role in shaping children's neurocognitive development. Clinical, epidemiologic, and basic science research suggests that two experiences relatively common in pregnancy--an unhealthy maternal diet and psychosocial…
Descriptors: Mothers, Prenatal Influences, Cognitive Development, Pregnancy
Romens, Sarah E.; Pollak, Seth D. – Journal of Child Psychology and Psychiatry, 2012
Background: Child maltreatment is associated with heightened risk for depression; however, not all individuals who experience maltreatment develop depression. Previous research indicates that maltreatment contributes to an attention bias for emotional cues, and that depressed individuals show attention bias for sad cues. Method: The present study…
Descriptors: Cues, Child Abuse, Depression (Psychology), Self Control
Thomason, Moriah E.; Hamilton, J. Paul; Gotlib, Ian H. – Journal of Child Psychology and Psychiatry, 2011
Background: Responses to stress vary greatly in young adolescents, and little is known about neural correlates of the stress response in youth. The purpose of this study was to examine whether variability in cortisol responsivity following a social stress test in young adolescents is associated with altered neural functional connectivity (FC) of…
Descriptors: Adolescents, Brain, Stress Variables, Diagnostic Tests
Kujawa, Autumn; Hajcak, Greg; Torpey, Dana; Kim, Jiyon; Klein, Daniel N. – Journal of Child Psychology and Psychiatry, 2012
Background: The late positive potential (LPP) is an event-related potential component that indexes selective attention toward motivationally salient information and is sensitive to emotional stimuli. Few studies have examined the LPP in children. Depression has been associated with reduced reactivity to negative and positive emotional stimuli,…
Descriptors: Stimuli, Attention, Young Children, Depression (Psychology)
Wetter, Emily K.; El-Sheikh, Mona – Journal of Child Psychology and Psychiatry, 2012
Background: We assessed trajectories of children's internalizing symptoms as predicted by interactions among maternal internalizing symptoms, respiratory sinus arrhythmia (RSA) and child sex. Method: An ethnically and socioeconomically diverse sample of children (n = 251) participated during three study waves. Children's mean ages were 8.23 years…
Descriptors: Mothers, Psychopathology, Parent Child Relationship, Children
Tan, Patricia Z.; Forbes, Erika E.; Dahl, Ronald E.; Ryan, Neal D.; Siegle, Greg J.; Ladouceur, Cecile D.; Silk, Jennifer S. – Journal of Child Psychology and Psychiatry, 2012
Background: Reviews have highlighted anxious youths' affective disturbances, specifically, elevated negative emotions and reliance on ineffective emotion regulation strategies. However, no study has examined anxious youth's emotional reactivity and regulation in real-world contexts. Methods: This study utilized an ecological momentary assessment…
Descriptors: Anxiety Disorders, Emotional Response, Anxiety, Self Control
De Brito, Stephane A.; Viding, Essi; Sebastian, Catherine L.; Kelly, Philip A.; Mechelli, Andrea; Maris, Helen; McCrory, Eamon J. – Journal of Child Psychology and Psychiatry, 2013
Background: Childhood maltreatment is strongly associated with increased risk of psychiatric disorder. Previous neuroimaging studies have reported atypical neural structure in the orbitofrontal cortex, temporal lobe, amygdala, hippocampus and cerebellum in maltreated samples. It has been hypothesised that these structural differences may relate to…
Descriptors: Psychopathology, Child Abuse, Cognitive Ability, Risk
Schmitz, Julian; Kramer, Martina; Tuschen-Caffier, Brunna; Heinrichs, Nina; Blechert, Jens – Journal of Child Psychology and Psychiatry, 2011
Background: Psychophysiological hyperresponsiveness to social-evaluative stress plays a key role in current theories of social phobia (SP). Owing to the early onset of this disorder, the study of children with SP can help to improve etiological models. However, research to date has failed to clarify whether children with SP are physiologically…
Descriptors: Anxiety Disorders, Metabolism, Children, Infants
Pickles, Andrew; Hill, Jonathan; Breen, Gerome; Quinn, John; Abbott, Kate; Jones, Helen; Sharp, Helen – Journal of Child Psychology and Psychiatry, 2013
Background: The low expression polymorphism of the MAOA gene in interaction with adverse environments (G × E) is associated with antisocial behaviour disorders. These have their origins in early life, but it is not known whether MAOA G × E occurs in infants. We therefore examined whether MAOA G × E predicts infant anger proneness, a temperamental…
Descriptors: Antisocial Behavior, Behavior Disorders, Infants, Genetics
Banaschewski, Tobias; Jennen-Steinmetz, Christine; Brandeis, Daniel; Buitelaar, Jan K.; Kuntsi, Jonna; Poustka, Luise; Sergeant, Joseph A.; Sonuga-Barke, Edmund J.; Frazier-Wood, Alexis C.; Albrecht, Bjorn; Chen, Wai; Uebel, Henrik; Schlotz, Wolff; van der Meere, Jaap J.; Gill, Michael; Manor, Iris; Miranda, Ana; Mulas, Fernando; Oades, Robert D.; Roeyers, Herbert; Rothenberger, Aribert; Steinhausen, Hans-Christoph; Faraone, Stephen V.; Asherson, Philip – Journal of Child Psychology and Psychiatry, 2012
Background: Emotional lability (EL) is commonly seen in patients with attention-deficit/hyperactivity disorder (ADHD). The reasons for this association remain currently unknown. To address this question, we examined the relationship between ADHD and EL symptoms, and performance on a range of neuropsychological tasks to clarify whether EL symptoms…
Descriptors: Attention Deficit Hyperactivity Disorder, Siblings, Severity (of Disability), Patients
Doehnert, Mirko; Brandeis, Daniel; Schneider, Gudrun; Drechsler, Renate; Steinhausen, Hans-Christoph – Journal of Child Psychology and Psychiatry, 2013
Background: This longitudinal electrophysiological study investigated the course of multiple impaired cognitive brain functions in attention-deficit/hyperactivity disorder (ADHD) from childhood to adulthood by comparing developmental trajectories of individuals with ADHD and typically developing controls. Methods: Subjects with ADHD ("N"…
Descriptors: Attention Deficit Hyperactivity Disorder, Physiology, Genetics, Longitudinal Studies
