Background and Methods: We report historical information from longitudinal data held in the British Isles Rett Syndrome Survey (BIRSS) concerning women of at least 40 years. This information, including comments on the quality of care, has been provided by families, carers, and clinicians. Results: Information was available on 30 women with a…

The equilibrium potential of an ion species is a crucial concept for medical students, as it is a prerequisite to fully understanding the pathophysiology of K+ imbalances (hyperkalemia and hypokalemia) in clinical practice. However, it remains a challenging concept because current medical physiology textbooks are too simplistic and overlook…

Background: Cognitive load theory is widely used in educational research and instructional design, which relies heavily on conceptual constructs and measurement instruments of cognitive load. Due to its implicit nature, cognitive load is usually measured by other related instruments, such as commonly-used self-report scales of mental effort or…

Background: Accumulating evidence substantiates the adverse impact of psychological maltreatment on children's emotion regulation. Nevertheless, scant research has explored the relationship between psychological maltreatment and automatic emotion regulation (AER), along with its underlying neural mechanisms. Objective: This study aims to…

Elevated "neural noise" has been advanced as an explanation of autism and autistic sensory experiences. However, functional neuroimaging measures of neural noise may be vulnerable to contamination by recording noise. This study explored variability of electrophysiological responses to tones of different intensities in 127 autistic and 79…

Background: Measures that assess muscle strength and its development, either voluntarily or involuntarily, are important in the clinical and research context. The main aim of this study was to verify the interday reliability and the minimum detectable change (MDC) of the knee extensors muscles torque using evoked contractions and explosive…

Autism spectrum disorder is a neurodevelopmental disorder characterized by a wide range of behavioral alterations, including impaired social interaction and repetitive behaviors. Numerous pharmacological interventions have been developed for autism spectrum disorder, often proving ineffective and accompanied by a multitude of side effects. The gut…

Self-regulation is an essential component of school readiness. Although in educational contexts self-regulation is typically defined in terms of volitional processes, it also encompasses the activity of neurophysiological systems, including the parasympathetic nervous system (PNS). In a prospective longitudinal study, 102 preschoolers (M[subscript…

Recent studies show that oxidative stress has an important role in the etiology of autism. In our study, Nrf2, which is the main regulator of cellular antioxidant response, and Keap1 and Gsk-3[beta], which are the main proteins that regulate this pathway, were compared between children with autism and healthy controls. To the best of our…

Objective: This study examined the effects of a college mindfulness course on vital-signs and Five Facet Mindfulness Questionnaire (FFMQ) scores. Participants: Two independent groups of 20 students were enrolled in the mindfulness course during the Fall 2018 ("Trial 1") and Spring 2019 ("Trial 2") semesters. Methods: Blood…

This paper presents a review of the literature pertaining to exam anxiety, highlighting findings from empirical studies, theoretical frameworks, and practical strategies. Exam anxiety is a pervasive issue affecting students worldwide, impacting academic performance and psychological well-being. This review explores the causes, manifestations, and…

The purpose of this study is to determine the effect of 8 weeks of HRV (Heart Rate Variability) training on the happiness and coherence levels of university students. According to this purpose, 20 sports management students from the same class volunteered to participate in the study. 10 students were selected randomly as the experimental group…

Artificial placentas (APs) are technologies that mimic the human placenta to treat extremely preterm infants. Being an invasive and risky technology, it will raise important ethical questions for human trials. Hence, in this Topic Piece we provide a blueprint of further issues to investigate. First, counselling will have the double role of…

Menstruation impacts participation in adventurous activities but there are gaps in reported research on the views and perspectives of men. This study examines the ways in which people who menstruate (inclusive of the LGBTQIA+ community) perceive and report attitudes to menstruation and the menstrual cycle by men, and the ways in which cis-males…

We present an alternative to the traditional classroom lecture on the topics of metabolic scaling, allometric relationships between metabolic rate (MR) and body size, and reasons for rejecting Rubner's surface "law," concepts that students have described as challenging, counterintuitive, and/or mathematical. In groups, students work with…