The goal of this series of experiments was to develop an operant choice procedure to examine rapidly the punishing effects of intravenous drugs in rats. First, the cardiovascular effects of experimenter-administered intravenous histamine, a known aversive drug, were assessed to determine a biologically active dose range. Next, rats responded on…

Three experiments using human participants varied the distribution of point-gain reinforcers or point-loss punishers in two-alternative signal-detection procedures. Experiment 1 varied the distribution of point-gain reinforcers for correct responses (Group A) and point-loss punishers for errors (Group B) across conditions. Response bias varied…

From its inception in the 1930s until very recent times, the cumulative recorder was the most widely used measurement instrument in the experimental analysis of behavior. It was an essential instrument in the discovery and analysis of schedules of reinforcement, providing the first real-time analysis of operant response rates and patterns. This…

The relation between the rate of a response ("B") and the rate of its reinforcement ("R") is well known to be approximately hyperbolic: B = kR/(R + R[subscript o]), where k represents the maximum response rate, and R[subscript o] indicates the rate of reinforcers that will engender a response rate equal to half its maximum value. A review of data…