Although most males with a 49,XXXXY karyotype will have significant mental retardation, the case of an affected boy having mild-cognitive and motor delays and age-appropriate adaptive skills at 59 months is presented. Guarded optimism may be justified in affected males demonstrating close to or age-appropriate developmental skills through early…

Behavioral intentions of 100 families regarding out-of-home placement for their child or early adolescent with severe handicaps were tracked 4 times over 6 years with the Placement Tendency Index, to assess the dynamics of family behavioral change. The index had long-term modest predictive capacity but increased predictive utility over shorter…