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A Comparative Analysis of the Full and Short Versions of the Social Responsiveness Scale in Estimating an Established Autism Risk Factor Association in ECHO: Do We Get the Same Estimates?
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Marisa A. Patti; Xuejuan Ning; Mina Hosseini; Lisa A. Croen; Robert M. Joseph; Margaret R. Karagas; Christine Ladd-Acosta; Rebecca Landa; Daniel S. Messinger; Craig J. Newschaffer; Ruby Nguyen; Sally Ozonoff; T. Michael O'Shea; Rebecca J. Schmidt; Cindy O. Trevino; Kristen Lyall – Journal of Autism and Developmental Disorders, 2025
Purpose: Prior work developed a shortened 16-item version of the Social Responsiveness Scale (SRS), a quantitative measure of social communication and autism spectrum disorder (ASD)-related traits. However, its properties for use in risk factor estimation have not been fully tested compared to the full SRS. We compared the associations between…
Descriptors: Autism Spectrum Disorders, Risk, Pregnancy, Premature Infants
Effect of Anesthesia during Pregnancy, Delivery, and Childhood on Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
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Simin He; Feixiang Zhou; Gang Tian; Yiran Cui; Yan Yan – Journal of Autism and Developmental Disorders, 2024
To investigate the association between exposure to anesthesia during three periods of pregnancy, delivery, and childhood and autism spectrum disorder (ASD). PubMed, Scopus, Web of Science, Embase, Google Scholar, PsycArticles, and PsycINFO were searched from the date of database inception to 1 December 2022. Studies reported the association…
Descriptors: Pregnancy, Anesthesiology, Autism Spectrum Disorders, Medical Services
Severity of Autism Spectrum Disorder Symptoms Associated with De Novo Variants and Pregnancy-Induced Hypertension
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Xiaomeng Wang; Zhengbao Ling; Tengfei Luo; Qiao Zhou; Guihu Zhao; Bin Li; Kun Xia; Jinchen Li – Journal of Autism and Developmental Disorders, 2024
Genetic factors, particularly, de novo variants (DNV), and an environment factor, exposure to pregnancy-induced hypertension (PIH), were reported to be associated with risk of autism spectrum disorder (ASD); however, how they jointly affect the severity of ASD symptom is unclear. We assessed the severity of core ASD symptoms affected by functional…
Descriptors: Severity (of Disability), Symptoms (Individual Disorders), Autism Spectrum Disorders, Genetics
Brief Report: Pregnancy, Birth and Infant Feeding Practices: A Survey-Based Investigation into Risk Factors for Autism Spectrum Disorder
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Whitely, Aleesha; Shandley, Kerrie; Huynh, Minh; Brown, Christine M.; Austin, David W.; Bhowmik, Jahar – Journal of Autism and Developmental Disorders, 2022
A succession of interconnected environmental factors is believed to contribute substantially to the development of autism spectrum disorder (ASD). This exploratory study therefore aims to identify potential risk factors for ASD that are associated with pregnancy, birth and infant feeding. Demographic and health-related data on children aged…
Descriptors: Pregnancy, Birth, Infants, Nutrition
The Association between Threatened Miscarriage and Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder in Offspring by Age 14 Years
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Daire Buckley; Ali S. Khashan; Fergus P. McCarthy; Karen O'Connor; Gillian M. Maher – Journal of Autism and Developmental Disorders, 2025
Objective: To examine the association between threatened miscarriage, and neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in offspring by age 14 years. Methods: We used data from the Millennium Cohort Study, a nationally representative longitudinal study of children born in…
Descriptors: Autism Spectrum Disorders, Neurodevelopmental Disorders, Attention Deficit Hyperactivity Disorder, Pregnancy
Autistic People's Perinatal Experiences I: A Survey of Pregnancy Experiences
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Sarah Hampton; Carrie Allison; Simon Baron-Cohen; Rosemary Holt – Journal of Autism and Developmental Disorders, 2024
Qualitative studies of autistic people's pregnancy experiences have indicated sensory and communication related barriers to accessing adequate prenatal healthcare. However, quantitative work on the topic is scarce. This online survey study explored pregnancy experiences among 417 autistic and 524 non-autistic people. Compared with non-autistic…
Descriptors: Autism Spectrum Disorders, Pregnancy, Adults, Parents with Disabilities
Examining Associations between Prenatal Biomarkers of Oxidative Stress and ASD-Related Outcomes Using Quantile Regression
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Carey, Meghan E.; Rando, Juliette; Melnyk, Stepan; James, S. Jill; Snyder, Nathaniel; Salafia, Carolyn; Croen, Lisa A.; Fallin, M. Daniele; Hertz-Picciotto, Irva; Volk, Heather; Newschaffer, Craig; Lyall, Kristen – Journal of Autism and Developmental Disorders, 2023
We examined associations between prenatal oxidative stress (OS) and child autism-related outcomes. Women with an autistic child were followed through a subsequent pregnancy and that younger sibling's childhood. Associations between glutathione (GSH), glutathione disulfide (GSSG), 8-oxo-deoxyguanine (8-OHdG), and nitrotyrosine and younger sibling…
Descriptors: Physiology, Prenatal Influences, Autism Spectrum Disorders, Pregnancy
Maternal Mid-Gestation Cytokine Dysregulation in Mothers of Children with Autism Spectrum Disorder
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Casey, S.; Carter, M.; Looney, A. M.; Livingstone, V.; Moloney, G.; O'Keeffe, G. W.; Taylor, R. S.; Kenny, L. C.; McCarthy, F. P.; McCowan, L. M. E.; Thompson, J. M. D.; Murray, D. M. – Journal of Autism and Developmental Disorders, 2022
Autism spectrum disorder (ASD) is a developmental disorder characterised by deficits in social interactions and communication, with stereotypical and repetitive behaviours. Recent evidence suggests that maternal immune dysregulation may predispose offspring to ASD. Independent samples t-tests revealed downregulation of IL-17A concentrations in…
Descriptors: Mothers, Children, Autism, Pervasive Developmental Disorders
Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-Analysis and Meta-Regression
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Liu, Xian; Zou, Mingyang; Sun, Caihong; Wu, Lijie; Chen, Wen-Xiong – Journal of Autism and Developmental Disorders, 2022
We systematically reviewed the evidence on the association between maternal folic acid supplementation and the risk of offspring's autism spectrum disorders (ASD). A total of 10 studies with 23 sub-studies (9795 ASD cases) were included. Folic acid supplementation during early pregnancy was associated with a lower risk of offspring's ASD [OR 0.57,…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Mothers
Maternal Exposure to Pesticides and Risk of Autism Spectrum Disorders in Offspring: A Meta-Analysis
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Wang, Li; Tang, Shiming; Wu, Songjie; Yao, Lihua; Su, Dezhen; Wang, Ying – Journal of Autism and Developmental Disorders, 2022
This meta-analysis was conducted to estimate the overall association between maternal exposure to pesticides and risk of ASD in offspring. PubMed, EMBASE, Web of Science, and the PsycINFO were searched until December 30, 2020 to include eligible studies. Eight studies with 50,426 participants, 5810 of whom had ASD, were involved in the study.…
Descriptors: Mothers, Pregnancy, Prenatal Influences, Poisoning
Prenatal Androgen Exposure and Traits of Autism Spectrum Disorder in the Offspring: Odense Child Cohort
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Palm, Camilla V. B.; Glintborg, Dorte; Find, Laura G.; Larsen, Pia V.; Dalgaard, Cilia M.; Boye, Henriette; Jensen, Tina K.; Dreyer, Anja F.; Andersen, Marianne S.; Bilenberg, Niels – Journal of Autism and Developmental Disorders, 2023
Fetal androgen exposure may be associated with autism spectrum disorder (ASD). We studied 1777 mother-child pairs in the prospective Odense Child Cohort. Prenatal androgen exposure was assessed by maternal 3rd trimester testosterone concentrations, maternal polycystic ovary syndrome (PCOS), and 3 months offspring anogenital distance. ASD traits…
Descriptors: Prenatal Influences, Autism Spectrum Disorders, Correlation, Mothers
Long-Term Memory of Sensory Experiences from the First Pregnancy, Its Peri-Partum and Post-Partum in Women with Autism Spectrum Disorders without Intellectual Disabilities: A Retrospective Study
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Benedetta Demartini; Veronica Nisticò; Serena Limonta; Vincenza Tarantino; Giulia Stefanelli; Federica Calistro; Laura Giambanco; Raffaella Faggioli; Orsola Gambini; Patrizia Turriziani – Journal of Autism and Developmental Disorders, 2024
Purpose: To explore the recalled experience of pregnancy and motherhood in women diagnosed with Autism Spectrum Disorders (ASD) without intellectual disabilities, focusing on sensory perceptions and mood. Methods: We retrospectively evaluated, through an ad-hoc structured interview, the sensory sensitivity during the pre-partum, the peri-partum,…
Descriptors: Long Term Memory, Pregnancy, Child Rearing, Mothers
Sulfate Deficiency as a Risk Factor for Autism
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Williams, Richard J. – Journal of Autism and Developmental Disorders, 2020
This is a study of water and beverages consumed during pregnancy by mothers of children with autism. Materials included vials for water samples and a survey to describe the water and beverages. Samples were tested for sulfate and surveys evaluated for average daily levels. Results were stratified for selected regions of the United States. Areas…
Descriptors: Autism, Pervasive Developmental Disorders, Mothers, Pregnancy
Pre- and Perinatal Risk Factors for Youth with Autism Spectrum Disorder versus Youth with Other Mental Health Disorders
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R. Enrique Varela; Emily Vinet; Jodi Kamps; Laura Niditch – Journal of Autism and Developmental Disorders, 2024
Research has linked pre- and perinatal complications (PPCs) with increased risk for autism spectrum disorder (ASD). However, PPCs are also known risk factors for other mental health disorders. This study explored which PPCs are specific risk factors for ASD, as opposed to other forms of psychopathology, among a large sample of clinically-referred…
Descriptors: Youth, Autism Spectrum Disorders, Control Groups, Mental Disorders
Associations between Broader Autism Phenotype and Dietary Intake: A Cross-Sectional Study (Japan Environment & Children's Study)
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Hirokawa, Kumi; Kimura, Takashi; Ikehara, Satoyo; Honjo, Kaori; Ueda, Kimiko; Sato, Takuyo; Iso, Hiroyasu; Kishi, Reiko; Yaegashi, Nobuo; Hashimoto, Koichi; Mori, Chisato; Ito, Shuichi; Yamagata, Zentaro; Inadera, Hidekuni; Kamijima, Michihiro; Heike, Toshio; Iso, Hiroyasu; Shima, Masayuki; Kawai, Yasuaki; Suganuma, Narufumi; Kusuhara, Koichi; Katoh, Takahiko – Journal of Autism and Developmental Disorders, 2020
The purpose of the present study was to investigate associations of dietary intake including vitamin D, folate, and n-3 and n-6 polyunsaturated fatty acids (PUFA) in pregnant women with broad autism phenotype (BAP). The Japan Environment and Children's Study is a government-funded birth cohort study. All complete data of 92,011 were analyzed. The…
Descriptors: Eating Habits, Dietetics, Nutrition, Pregnancy
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