As part of their ongoing work, the Board on Higher Education and Workforce and the Roundtable on Mentorship, Well-being, and Professional Development of the National Academies of Sciences, Engineering, and Medicine convened an in-person and online workshop on Empowering Senior Higher Education Leaders in Developing an Equitable Research Ecosystem on April 30, 2024, on the campus of Duke University in Durham, North Carolina. The workshop sought to highlight the roles senior leaders (e.g., presidents, provosts, and deans) play in embodying an equitable research ecosystem -- sharing strategies and resources and allowing participants to develop actionable plans that integrate mentorship, well-being, and professional development for graduate and professional students and postdoctoral scholars. This publication summarizes the presentations and discussion of the workshop.