Previous research indicates that postsecondary educational experience (PSE) predicts successful employment outcomes for transition-aged youth with disabilities. Using data on supported employment services from the Rehabilitative Services Administration, this study compared employment rates and outcomes for young adults with Autism Spectrum Disorder (ASD) with different levels of education who received supported employment services. The study also analyzed the cost-effectiveness and cost-efficiency of vocational rehabilitation (VR) services provided to these youth. Findings indicate that young adults with PSE experienced increased rates of employment, earned greater weekly wages, and worked more weekly hours than individuals with ASD with less education. VR services provided to youth with ASD in the PSE group were more cost-effective and were ultimately cost-efficient, provided that individuals maintained employment for 16 months.