Evidence on the effectiveness of telemedicine in coaching parents of autistic children using naturalistic developmental early interventions is limited. This review aimed to examine the literature on the effectiveness of telemedicine on children's social communication following parent-mediated naturalistic developmental early interventions. A total of nine studies were identified. Intervention characteristics, outcomes, and research quality were assessed. Findings suggest insufficient evidence for the effectiveness of telemedicine on child social communication. All the included studies were at high risk of bias in at least one quality indicator of the risk of bias tools. More high-quality research is required to examine the effectiveness of telemedicine applications on child social communication to support access and continuity of early intervention services.