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Program Evaluation3
Research Design3
Research Methodology3
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Randomized Controlled Trials2
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Research Synthesis Methods3
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Higgins, Julian P. T.2
Ramsay, Craig2
Reeves, Barnaby C.2
Shea, Beverley2
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Valentine, Jeffrey C.2
Deeks, Jonathan J.1
Thompson, Simon G.1
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Wells, George A.1
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Issues Relating to Study Design and Risk of Bias When Including Non-Randomized Studies in Systematic Reviews on the Effects of Interventions
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Higgins, Julian P. T.; Ramsay, Craig; Reeves, Barnaby C.; Deeks, Jonathan J.; Shea, Beverley; Valentine, Jeffrey C.; Tugwell, Peter; Wells, George – Research Synthesis Methods, 2013
Non-randomized studies may provide valuable evidence on the effects of interventions. They are the main source of evidence on the intended effects of some types of interventions and often provide the only evidence about the effects of interventions on long-term outcomes, rare events or adverse effects. Therefore, systematic reviews on the effects…
Descriptors: Research Methodology, Intervention, Program Effectiveness, Program Evaluation
An Introduction to Methodological Issues When Including Non-Randomised Studies in Systematic Reviews on the Effects of Interventions
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Reeves, Barnaby C.; Higgins, Julian P. T.; Ramsay, Craig; Shea, Beverley; Tugwell, Peter; Wells, George A. – Research Synthesis Methods, 2013
Background: Methods need to be further developed to include non-randomised studies (NRS) in systematic reviews of the effects of health care interventions. NRS are often required to answer questions about harms and interventions for which evidence from randomised controlled trials (RCTs) is not available. Methods used to review randomised…
Descriptors: Research Methodology, Research Design, Health Services, Workshops
Issues Relating to Confounding and Meta-analysis When Including Non-Randomized Studies in Systematic Reviews on the Effects of Interventions
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Valentine, Jeffrey C.; Thompson, Simon G. – Research Synthesis Methods, 2013
Background: Confounding caused by selection bias is often a key difference between non-randomized studies (NRS) and randomized controlled trials (RCTs) of interventions. Key methodological issues: In this third paper of the series, we consider issues relating to the inclusion of NRS in systematic reviews on the effects of interventions. We discuss…
Descriptors: Research Design, Randomized Controlled Trials, Intervention, Bias