This is a practical guide for applying the Impact Threshold for a Confounding Variable and the Robustness of Inference to Replacement using the konfound packages in Stata and R as well as the R-shiny app. It includes motivation worked examples, and tutorials.

As traditionally conceived, publication bias arises from selection operating on a collection of individually unbiased estimates. A canonical form of such selection across studies (SAS) is the preferential publication of affirmative studies (i.e., those with significant, positive estimates) versus nonaffirmative studies (i.e., those with…