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Anhedonia Predicts Poorer Recovery among Youth with Selective Serotonin Reuptake Inhibitor Treatment-Resistant Depression
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McMakin, Dana L.; Olino, Thomas M.; Porta, Giovanna; Dietz, Laura J.; Emslie, Graham; Clarke, Gregory; Wagner, Karen Dineen; Asarnow, Joan R.; Ryan, Neal D.; Birmaher, Boris; Shamseddeen, Wael; Mayes, Taryn; Kennard, Betsy; Spirito, Anthony; Keller, Martin; Lynch, Frances L.; Dickerson, John F.; Brent, David A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: To identify symptom dimensions of depression that predict recovery among selective serotonin reuptake inhibitor (SSRI) treatment-resistant adolescents undergoing second-step treatment. Method: The Treatment of Resistant Depression in Adolescents (TORDIA) trial included 334 SSRI treatment-resistant youth randomized to a medication…
Descriptors: Outcomes of Treatment, Rating Scales, Adolescents, Depression (Psychology)
Clinical Presentation and Course of Depression in Youth: Does Onset in Childhood Differ from Onset in Adolescence?
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Birmaher, Boris; Williamson, Douglas E.; Dahl, Ronald E.; Axelson, David A.; Kaufman, Joan; Dorn, Lorah D.; Ryan, Neal D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To simultaneously and prospectively compare the clinical presentation, course, and parental psychiatric history between children and adolescents with major depressive disorder. Method: A group of prepubertal children (n = 46) and postpubertal adolescents (n = 22) were assessed with structured interviews for psychopathology and parental…
Descriptors: Psychiatry, Psychopathology, Adolescents, Anxiety
Psychosocial Functioning in Youths at High Risk to Develop Major Depressive Disorder.
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Birmaher, Boris; Bridge, Jeffrey A.; Williamson, Douglas E.; Brent, David A.; Dahl, Ronald E.; Axelson, David A.; Dorn, Lorah D.; Ryan, Neal D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To compare the psychosocial functioning of children and adolescents at high risk of major depressive disorder with youths with acute major depressive disorder and healthy controls. Method: High-risk (n = 57), major depressive disorder (n = 71), and healthy control (n = 48) youths and their families were recruited from 1987 to 1996 and…
Descriptors: Psychiatry, Psychopathology, Longitudinal Studies, Depression (Psychology)
Steady-State Pharmacokinetics of Bupropion SR in Juvenile Patients
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Daviss, W. Burleson; Perel, James M.; Rudolph, George R.; Axelson, David A.; Gilchrist, Richard; Nuss, Sharon; Birmaher, Boris; Brent, David A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To examine the steady-state pharmacokinetic properties of bupropion sustained release (SR) and their potential developmental differences in youths. Method: Eleven boys and eight girls aged 11 to 17 years old were prescribed bupropion SR monotherapy for attention-deficit/hyperactivity disorder (n = 16) and/or depressive disorders (n =…
Descriptors: Psychiatry, Pharmacology, Patients, Hyperactivity
Familial Transmission of Mood Disorders: Convergence and Divergence with Transmission of Suicidal Behavior.
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Brent, David A.; Oquendo, Maria; Birmaher, Boris; Greenhill, Laurence; Kolko, David; Stanley, Barbara; Zelazny, Jamie; Brodsky, Beth; Melhem, Nadine; Ellis, Steven P.; Mann, J. John – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: Both mood disorder and suicidal behavior are familial. In this study, the authors examine the factors associated with the familial transmission of these two related conditions to learn which are shared or unique risk factors for familial transmission. Method: The 285 offspring of 141 probands with mood disorder were studied. Proband and…
Descriptors: Psychiatry, Sexual Abuse, Risk, Path Analysis
Screening for Childhood Anxiety Symptoms in Primary Care: Integrating Child and Parent Reports.
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Wren, Frances J.; Bridge, Jeffrey A.; Birmaher, Boris – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: Parents' concerns typically determine the focus of a primary care visit. This study examined which information is lost if child reports are excluded from screening for anxiety. It also explores the use in primary care of the Screen for Child Anxiety Related Emotional Disorders (SCARED) and the Pediatric Symptom Checklist (PSC-17).…
Descriptors: Primary Health Care, Psychiatry, Parents, Check Lists
Treatment Guidelines for Children and Adolescents with Bipolar Disorder
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Kowatch, Robert A.; Fristad, Mary; Birmaher, Boris; Wagner, Karen Dineen; Findling, Robert L.; Hellander, Martha – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Clinicians who treat children and adolescents with bipolar disorder desperately need current treatment guidelines. These guidelines were developed by expert consensus and a review of the extant literature about the diagnosis and treatment of pediatric bipolar disorders. The four sections of these guidelines include diagnosis, comorbidity, acute…
Descriptors: Psychiatry, Identification, Guidelines, Adolescents
Citalopram Treatment of Pediatric Recurrent Abdominal Pain and Comorbid Internalizing Disorders: An Exploratory Study
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Campo, John V.; Perel, James; Lucas, Amanda; Bridge, Jeff; Ehmann, Mary; Kalas, Catherine; Monk, Kelly; Axelson, David; Birmaher, Boris; Ryan, Neal; Di Lorenzo, Carlo; Brent, David A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To assess the potential efficacy, tolerability, and safety of citalopram in the treatment of functional pediatric recurrent abdominal pain and comorbid internalizing disorders. Method: Twenty-five clinically referred children and adolescents with recurrent abdominal pain aged 7 to 18 years, inclusive, participated in a 12-week,…
Descriptors: Psychiatry, Pediatrics, Pain, Depression (Psychology)
First Episode of Depression in Children at Low and High Familial Risk for Depression
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Williamson, Douglas E.; Birmaher, Boris; Axelson, David A.; Ryan, Neal D.; Dahl, Ronald E. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To examine the development of first-onset major depressive disorder (MDD) in children at high and low familial risk for depression in a prospective study. Method: High-risk children (n = 76) who were free of any lifetime affective disorder and had at least one first-degree and one second-degree relative with a lifetime history of…
Descriptors: Psychiatry, Age, Schizophrenia, Mothers
Subjective Sleep Complaints in Pediatric Depression: A Controlled Study and Comparison with EEG Measures of Sleep and Waking
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Bertocci, Michele A.; Dahl, Ronald E.; Williamson, Douglas E.; Iosif, Ana-Maria; Birmaher, Boris; Axelson, David; Ryan, Neal D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: Children with major depressive disorder (MDD) often complain of sleep disturbances; however, polysomnographic studies have failed to find objective evidence of these disturbances. This article examines subjective sleep reports of children with MDD and healthy controls focusing on comparing subjective and objective sleep measures.…
Descriptors: Psychiatry, Depression (Psychology), Sleep, Medicine
Fluoxetine for the Treatment of Childhood Anxiety Disorders: Open-Label, Long-Term Extension to a Controlled Trial
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Clark, Duncan B.; Birmaher, Boris; Axelson, David; Monk, Kelly; Kalas, Catherine; Ehmann, Mary; Bridge, Jeffrey; Wood, D. Scott; Muthen, Bengt; Brent, David – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To assess the efficacy of fluoxetine for the long-term treatment of children and adolescents with anxiety disorders, including generalized anxiety disorder, separation anxiety disorder, and/or social phobia. Method: Children and adolescents (7-17 years old) with anxiety disorders were studied in open treatment for 1 year after they…
Descriptors: Psychiatry, Adolescents, Children, Separation Anxiety