Mediation analysis in Single Case Experimental Designs (SCEDs) evaluates intervention mechanisms for individuals. Despite recent methodological developments, no clear guidelines exist for maximizing power to detect the indirect effect in SCEDs. This study compares frequentist and Bayesian methods, determining (1) minimum required sample size to…

When designing cluster-randomized trials (CRTs), one important consideration is determining the proper sample sizes across levels and treatment conditions to cost-efficiently achieve adequate statistical power. This consideration is usually addressed in an optimal design framework by leveraging the cost structures of sampling and optimizing the…

Cluster-randomized trials have been widely used to evaluate the treatment effects of interventions on student outcomes. When interventions are implemented by teachers, researchers need to account for the nested structure in schools (i.e., students are nested within teachers nested within schools). Schools usually have a very limited number of…

Multisite cluster randomized trials (MCRTs), in which, the intermediate-level clusters (e.g., classrooms) are randomly assigned to the treatment or control condition within each site (e.g., school), are among the most commonly used experimental designs across a broad range of disciplines. MCRTs often align with the theory that programs are…

We have entered an era in which scientific evidence increasingly informs research practice and policy. As there is an exponential increase in the use of single-case experimental designs (SCEDs) to evaluate intervention effectiveness, there is accumulating evidence available for quantitative synthesis. Consequently, there is a growing interest in…

Simple matrix sampling planned missing (SMS PD) design, introduce missing data patterns that lead to covariances between variables that are not jointly observed, and create difficulties for analyses other than mean and variance estimations. Based on prior research, we adopted a new multigroup confirmatory factor analysis (CFA) approach to handle…

Optimal design of multisite randomized trials leverages sampling costs to optimize sampling ratios and ultimately identify more efficient and powerful designs. Past implementations of the optimal design framework have assumed that costs of sampling units are equal across treatment conditions. In this study, we developed a more flexible optimal…

Comprehensive evaluation of treatment effects is aided by considerations for moderated effects. In educational research, the combination of natural hierarchical structures and prevalence of group-administered or shared facilitator treatments often produces three-level partially nested data structures. Literature details planning strategies for a…

Changing criterion designs (CCD) are single-case experimental designs that entail a step-by-step approximation of the final level desired for a target behavior. Following a recent review on the desirable methodological features of CCDs, the current text focuses on an analytical challenge: the definition of an objective rule for assessing the…

Previous research found bias in the estimate of the overall fixed effects and variance components using multilevel meta-analyses of standardized single-case data. Therefore, we evaluate two adjustments in an attempt to reduce the bias and improve the statistical properties of the parameter estimates. The results confirm the existence of bias when…

Many experimental designs in educational and behavioral research involve at least one level of clustering. Clustering affects the precision of estimators and its impact on statistics in cross-sectional studies is well known. Clustering also occurs in longitudinal designs where students that are initially grouped may be regrouped in the following…

Sample size determination in multilevel randomized trials (MRTs) and multilevel regression discontinuity designs (MRDDs) can be complicated due to multilevel structure, monetary restrictions, differing marginal costs per treatment and control units, and range restrictions in sample size at one or more levels. These issues have sparked a set of…

When well-implemented, mediation analyses play a critical role in probing theories of action because their results help lay the ground work for the critical development of a treatment and the iterative advancement of theories that are foundational to a discipline. Despite strong interest in designs that incorporate mediation, few studies have…

Education experiments frequently assign students to treatment or control conditions within schools. Longitudinal components added in these studies (e.g., students followed over time) allow researchers to assess treatment effects in average rates of change (e.g., linear or quadratic). We provide methods for a priori power analysis in three-level…

Single subject (SS) designs are popular in educational and psychological research. There exist several statistical techniques designed to analyze such data and to address the question of whether an intervention has the desired impact. Recently, researchers have suggested that generalized additive models (GAMs) might be useful for modeling…