Phosphatase and tensin homolog-induced putative kinase 1 gene mutations have been associated with autosomal recessive early-onset Parkinson's disease. To date, no neuropathological reports have been published from patients with Parkinson's disease with both phosphatase and tensin homolog-induced putative kinase 1 gene copies mutated. We analysed…

The increasing use of diary methods calls for the development of appropriate statistical methods. For the resulting panel data, latent Markov models can be used to model both individual differences and temporal dynamics. The computational burden associated with these models can be overcome by exploiting the conditional independence relations…

Used patient encounter records completed by 445 medical students to determine whether a family medicine clerkship offered enough experience in ear, nose, and throat (ENT) conditions. Results, which were used for curriculum development, suggest that these students were receiving sufficient opportunities for some areas of ENT practice, but not for…

This paper gives a brief overview of how qualitative and quantitative interviews can be combined to get a fuller picture of a program and its outcomes. This concept is illustrated through a discussion of evaluations of the Employment Intervention Demonstration Program, a multi-site research demonstration project funded by the Substance Abuse…

Examined the factor structure of the Counselor Rating Form (CRF). Real clients (N=110) completed the CRF at the conclusion of counseling. The results suggest the existence of only one major factor underlying clients' perceptions of counselors. The one-factor model performed as well as the three-factor model. (Author/JAC)

It is argued that there is a benefit to applying techniques of exploratory data analysis (EDA) to program evaluation. The evaluation of a rehabilitation program for people with rheumatoid arthritis (20 subjects and 21 comparisons) through EDA supports the argument, indicating outcomes more precisely than conventional analysis of variance. (SLD)

Introduces strategy for evaluating how drugs, administered in varying doses, affect dependent variables (physiological, psychological, and social functioning and quality of life) that fluctuate in level. Tests hypotheses with statistics computed from benefit/harm scores, measuring longitudinal associations between dose and dependent variable…

An obvious source of information for assessing mental health program effectiveness comes from clients who have received the services and, indeed, much effort has been devoted to developing data collection instruments which are administered to clients upon completion of treatment. To assess the advantages and disadvantages of three treatment…

Describes the human patient simulator and discusses the value of this technology for undergraduate and graduate nursing education, research, and evaluation. Highlights include an example of the use of the simulator; critical incident nursing management as a framework for instruction using the simulator; and administrative considerations. (LRW)

Seventy clients participated in eight focus groups intended to identify clients' perceptions of vocational rehabilitation program strengths and weaknesses. The advantages of using a social science model applied to focus groups and the ways client empowerment can be a central theme in such efforts are explored. (SLD)

A pilot study in three rural Colorado communities that focused on health service delivery problems related to cancer concentrated on perceptions of community influentials, health care providers, and patients and their families. Results indicate that qualitative methods can identify crucial problems for most people without losing sight of outlier…