Background: Traditionally, meta-analysis of time-to-event outcomes reports a single pooled hazard ratio assuming proportional hazards (PH). For health technology assessment evaluations, hazard ratios are frequently extrapolated across a lifetime horizon. However, when treatment effects vary over time, an assumption of PH is not always valid. The…

Background: Meta-analysis refers to the statistical methods employed to combine results of several empirical studies in a topic of interest (Hedges & Olkin, 1985). Meta-analysis is often included in literature review studies to quantitatively analyze data from a collection of studies (Valentine et al., 2010). The statistical power of a…

Introduction: For tests reporting continuous results, primary studies usually provide test performance at multiple but often different thresholds. This creates missing data when performing a meta-analysis at each threshold. A standard meta-analysis (no imputation [NI]) ignores such missing data. A single imputation (SI) approach was recently…

Meta-analyses based on systematic literature reviews are commonly used to obtain a quantitative summary of the available evidence on a given topic. However, the reliability of any meta-analysis is constrained by that of its constituent studies. One major limitation is the possibility of small-study effects, when estimates from smaller and larger…

Bayesian statistical approaches to mixed treatment comparisons (MTCs) are becoming more popular because of their flexibility and interpretability. Many randomized clinical trials report multiple outcomes with possible inherent correlations. Moreover, MTC data are typically sparse (although richer than standard meta-analysis, comparing only two…

Federal standards established in 1997 allow respondents to select multiple-race categories. These new standards changed the single-race subgroup definitions that the government has required since 1977. Meta-analysis, research on long-term assessment trends, and other research involving historical comparisons must account for the definitional…

In meta-analysis, it is common to have dependent effect sizes, such as several effect sizes from the same sample but measured at different times. Cheung and Chan proposed the adjusted-individual and adjusted-weighted procedures to estimate the degree of dependence and incorporate this estimate in the meta-analysis. The present study extends the…

Using a set of scenarios derived from actual evaluation studies, this simulation study examines the reported influence of evaluation information on decision makers' potential actions. Each scenario described a context where one of three types of evaluation information (large-scale study data, case study data, or anecdotal accounts) is presented…

A Monte Carlo study considers the use of meta analysis with the Solomon four-group design. Experiment-wise Type I error properties and the relative power properties of Stouffer's Z in the Solomon four-group design are explored. Obstacles to conducting meta analysis in the Solomon design are discussed. (SLD)

The use of p-values in combining results of studies often involves studies that are potentially aberrant. This paper proposes a combined test that permits trimming some of the extreme p-values. The trimmed statistic is based on an inverse cumulative normal transformation of the ordered p-values. (SLD)

Substantial disagreement exists in the literature regarding which educational technology results in the highest cognitive gain for learners. In an attempt to resolve this dispute, we conducted a meta-analysis to decipher which teaching method, games and interactive simulations or traditional, truly dominates and under what circumstances. It was…

A content analysis was conducted of three educational research journals published by the American Educational Research Association to review the quantitative and qualitative techniques used in educational research. All articles appearing in these three journals from 1988 through 1995 (total n=1,715) were considered. Research methods were…