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Haijima, Asahi; Ichitani, Yukio – Learning & Memory, 2008
Retrograde and anterograde amnesic effects of excitotoxic lesions of the rat retrosplenial cortex (RS) and hippocampus (HPC) were investigated. To test retrograde amnesia, rats were trained with two-arm place discrimination in a radial maze 4 wk and 1 d before surgery with a different arm pair, respectively. In the retention test 1 wk after…
Descriptors: Control Groups, Intervals, Surgery, Memory
Wietrzych, Marta; Meziane, Hamid; Sutter, Anne; Ghyselinck, Norbert; Chapman, Paul F.; Chambon, Pierre; Krezel, Wojciech – Learning & Memory, 2005
Retinoid signaling has been recently shown to be required for mnemonic functions in rodents. To dissect the behavioral and molecular mechanisms involved in this requirement, we have analyzed the spatial and recognition working memory in mice carrying null mutations of retinoid receptors RAR[subscript [beta]] and RXR[subscript [gamma]]. Double…
Descriptors: Animals, Memory, Brain Hemisphere Functions, Perceptual Motor Learning