The purpose of this study was to determine the effect of the Jigsaw technique on nursing students' learning and retention of knowledge about employee safety. The study was conducted between December 2022 and January 2023 with 84 first-year students enrolled in the Nursing Department of a state university in a province of Turkey. Data were collected using the Descriptive Characteristics Form and Employee Safety Research/Test Instrument. During the study, the experimental group (n = 42) learned about employee safety using the Jigsaw technique, while the control group (n = 42) used the traditional method. Then, the students filled out the data collection forms (Post-test). Four weeks after the post-test, students again filled out the data collection forms to evaluate the retest of knowledge (Retest). The data were analysed with SPSS 22.0 package program. It was determined that the mean research/test instrument score of the experimental group in the employee safety post-test and retest was statistically significantly higher than the control group (p = 0.000). It was determined that the Jigsaw technique was effective in nursing students' learning of employee safety and retest of knowledge.