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Direct linkMo´nica I. Garci´a-Aranda; Marco Franco-Pe´rez; Angel Zamudio-Medina – Journal of Chemical Education, 2023
Heterocyclic compounds are an integral part of research, particularly in the pharmaceutical field. The synthesis of such compounds in an undergraduate laboratory can help students understand the relevance and importance of their field of study. Our experimental activity introduces a novel procedure to synthesize coumarin, a heterocyclic formed by…
Descriptors: Undergraduate Students, College Science, Chemistry, Laboratory Experiments
Siddiqui, Khawar S.; Poljak, Anne; Ertan, Haluk; Bridge, Wallace – Biochemistry and Molecular Biology Education, 2022
Determination of enzyme activity is crucial for discovery, research, and development in life sciences. The activity of enzymes is routinely determined using spectrophotometric assays that measure rates of substrate consumption or product formation. Though colorimetric-based detection systems are simple, rapid, and economical to perform, the…
Descriptors: Biochemistry, Biological Sciences, College Science, Heat
Faville, Scott C.; Harris-Hamdscomb, Kes; Harker, Owain; Mattison, Stephanie; Tamorite, Hajie; Bristowe, Joshua; Daly, Daniel; Ege, Raissa; He, Haoyuan; Jones, Julian; McCorkindale, Abby; Mei, Kerry; Monson, Ashleigh; Moree, Lana; Perkovic, Finley; Rickerby, Georgia; Robinson, Jack; Rudkin, Felix; Whibley, Luke; Worthington, Rebecca; Ennis, Courtney; de la Harpe, Sara; Brind, Thomasin; Hopkins, Andrew; Winefield, Kaleb; Hendrickx, Sarah; Caljon, Guy; Perry, Benjamin; Vernall, Andrea J. – Journal of Chemical Education, 2022
An undergraduate laboratory was developed as part of the Drugs for Neglected Diseases "initiative's" Open Synthesis Network. This activity aimed to develop new compounds efficacious against visceral leishmaniasis. Students successfully synthesized, purified, and characterized ten different benzoxazole amides that were sent for biological…
Descriptors: College Science, Undergraduate Students, Laboratory Experiments, Diseases
Waleed Alahmad; Somsak Pianwanit; Luxsana Dubas; Charoenkwan Kraiya – Journal of Chemical Education, 2023
The COVID-19 pandemic has significantly affected teaching processes worldwide, particularly in laboratory-intensive courses. To adapt, online experiments have been implemented globally. In response, educators at the Department of Chemistry, Chulalongkorn University, developed a Lab@Home chemistry experiment for their general chemistry lab course…
Descriptors: Chemistry, Science Laboratories, Laboratory Experiments, Scientific Concepts
Bracker, Rachel; Dominguez, Kimberly; Stender, Anthony S. – Journal of Chemical Education, 2020
Nanoparticles are an increasingly important tool in chemistry research, but currently there are few opportunities for chemistry students to work with nanoparticles in undergraduate analytical courses. In this exercise, designed for an analytical or instrumental analysis lab course, students have the opportunity to work with solutions of silver…
Descriptors: Chemistry, Undergraduate Students, Science Activities, Science Instruction
Download full textGerard G. Dumancas; Noemi Carreto; Oliver Generalao; Guoyi Ke; Ghalib Bello; Arnold Lubguban; Roberto Malaluan – Journal of Chemical Education, 2023
Chemometric techniques such as partial least-squares (PLS) regression have been applied with huge success to a wide array of chemical problems including multicomponent analysis of analytes in complex mixtures. Despite this, there are few examples of laboratory pedagogical exercises that involve students in the acquisition of chemical data from…
Descriptors: Undergraduate Students, College Science, Chemistry, Science Laboratories
Tyler A. Shaffer; Carlos U. Herrada; Avery M. Walker; Laura D. Casto-Boggess; Lisa A. Holland; Timothy R. Johnson; Megan E. Jones; Yousef S. Elshamy – Journal of Chemical Education, 2023
Electrophoresis is integral to analytical and biochemistry experiences in undergraduate education; however, fundamental principles of the method are often taught in upper-level laboratories through hands-on experiences. A laboratory activity is reported that teaches the concepts of electrophoretic mobility and electroosmotic flow. A single…
Descriptors: Chemistry, Science Instruction, Teaching Methods, Cost Effectiveness
Larouche, Olivier; Jolicoeur, Ludovic; Calosi, Piero – Journal of Biological Education, 2020
Changes in environmental conditions can have a profound impact on organismal processes. For aquatic organisms, changes in dissolved oxygen concentration can have major repercussions, notably for physiological processes that have high long-term energetic costs and are more likely to rely on aerobic metabolic pathways. Here we propose a simple…
Descriptors: College Science, Science Activities, Marine Biology, Science Instruction
De Groef, Bert; Grommen, Sylvia V. H. – Biochemistry and Molecular Biology Education, 2019
The laboratory exercise described here aims to provide a relevant context for learning basic DNA techniques in an introductory animal science course at tertiary level. In two 4-hr laboratory sessions, students assess the suitability of bulls for inclusion in a gene-assisted selection program for A2 [beta]-casein by genotyping commercial bull…
Descriptors: Genetics, Molecular Biology, Animal Husbandry, Introductory Courses
Dounay, Amy B.; O'Donnell, Martin J.; Samaritoni, J. Geno; Popiolek, Lukasz; Schirch, Douglas; Biernasiuk, Anna; Malm, Anna; Lamb, Isaac W.; Mudrack, Kristen; Rivera, Daniel G.; Ojeda, Gerardo M.; Scott, William L. – Journal of Chemical Education, 2019
An experiment for the synthesis of N-acyl derivatives of natural amino acids has been developed as part of the Distributed Drug Discovery (D3) program. Students use solid-phase synthesis techniques to complete a three-step, combinatorial synthesis of six products, which are analyzed using LC-MS and NMR spectroscopy. This protocol is suitable for…
Descriptors: Organic Chemistry, Laboratory Experiments, Science Experiments, Pharmacology
Nyutu, Eva N.; Cobern, William W.; Pleasants, Brandy A. S. – Journal of Biological Education, 2019
Introductory laboratory courses are a standard component of undergraduate science programmes and historically taught using direct instruction/confirmatory lab models. Previous studies have shown that inquiry-based labs enhance student engagement in science courses. However, research on how direct instruction introductory lab courses effectively…
Descriptors: Learner Engagement, Direct Instruction, Undergraduate Students, Microbiology
Geisert, Rodney D.; Smith, Michael F.; Schmelzle, Amanda L.; Green, Jonathan A. – Advances in Physiology Education, 2018
In this teaching laboratory, the students are directed in an exercise that involves designing and performing an experiment to determine estrogen's role in regulating delayed implantation (diapause) in female rats. To encourage active participation by the students, a discussion question is provided before the laboratory exercise in which each…
Descriptors: Birth, Biology, Animals, Science Instruction
Cybulskis, Viktor J.; Gawecki, Piotr; Zvinevich, Yury; Gounder, Rajamani; Ribeiro, Fabio H. – Journal of Chemical Education, 2021
A versatile and portable apparatus was developed to demonstrate exciting visual displays of catalytic phenomena that introduce basic concepts in catalysis, renewable energy, and chemical safety, in order to pique scientific curiosity in a variety of audiences including middle and high school students, undergraduate and graduate students, and the…
Descriptors: Science Instruction, Chemistry, Scientific Concepts, Concept Formation
Wagner, Eugene P., II – Journal of Chemical Education, 2016
A student laboratory experiment to investigate the intrinsic and extrinsic bandgaps, dopant materials, and diode design in light-emitting diodes (LEDs) is presented. The LED intrinsic bandgap is determined by passing a small constant current through the diode and recording the junction voltage variation with temperature. A second visible…
Descriptors: Light, Electronics, College Science, Science Instruction
Procko, Carl; Morrison, Steven; Dunar, Courtney; Mills, Sara; Maldonado, Brianna; Cockrum, Carlee; Peters, Nathan Emmanuel; Huang, Shao-shan Carol; Chory, Joanne – CBE - Life Sciences Education, 2019
Next-generation sequencing (NGS)-based methods are revolutionizing biology. Their prevalence requires biologists to be increasingly knowledgeable about computational methods to manage the enormous scale of data. As such, early introduction to NGS analysis and conceptual connection to wet-lab experiments is crucial for training young scientists.…
Descriptors: Undergraduate Students, Data Analysis, Biology, Information Science
